276948

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-YafN
Location 2293830..2294352 Replicon chromosome
Accession NZ_CP122457
Organism Salmonella enterica subsp. enterica strain TZ282

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag QCX26_RS11080 Protein ID WP_079984302.1
Coordinates 2293830..2294114 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID V1H457
Locus tag QCX26_RS11085 Protein ID WP_000885424.1
Coordinates 2294104..2294352 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCX26_RS11060 (2289905) 2289905..2291413 - 1509 WP_079984305.1 FAD-dependent oxidoreductase -
QCX26_RS11065 (2291458) 2291458..2291946 + 489 WP_283880732.1 MarR family winged helix-turn-helix transcriptional regulator -
QCX26_RS11070 (2292139) 2292139..2293212 + 1074 WP_079984303.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
QCX26_RS11075 (2293270) 2293270..2293659 - 390 WP_000194089.1 RidA family protein -
QCX26_RS11080 (2293830) 2293830..2294114 - 285 WP_079984302.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QCX26_RS11085 (2294104) 2294104..2294352 - 249 WP_000885424.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QCX26_RS11090 (2294478) 2294478..2294669 - 192 Protein_2168 hypothetical protein -
QCX26_RS11095 (2295034) 2295034..2295150 + 117 Protein_2169 IS110 family transposase -
QCX26_RS11100 (2295219) 2295219..2295551 + 333 WP_079984301.1 DUF1493 family protein -
QCX26_RS11105 (2296427) 2296427..2297335 + 909 WP_079798353.1 LysR family transcriptional regulator -
QCX26_RS11110 (2297509) 2297509..2298489 + 981 WP_079984298.1 nitronate monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2291458..2300207 8749


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11105.87 Da        Isoelectric Point: 10.6500

>T276948 WP_079984302.1 NZ_CP122457:c2294114-2293830 [Salmonella enterica subsp. enterica]
MTYKLAFNESALKEWKKLGHTIQEQFKKKLRERLENPRVPTSQLHGRKDQYKIKLRGAGYRLVYSVEDEIITVTVIGVGK
RENDAVYKMTRHRS

Download         Length: 285 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.32 Da        Isoelectric Point: 3.9820

>AT276948 WP_000885424.1 NZ_CP122457:c2294352-2294104 [Salmonella enterica subsp. enterica]
MAFQILTTTAASITELKRDPMGTFNAGDGAPVAILNRNEPAFYCVPPALYAHLMDILEDEELGRIIDERANERVIEVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0WPN5

References