276946

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 845715..846340 Replicon chromosome
Accession NZ_CP122457
Organism Salmonella enterica subsp. enterica strain TZ282

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QCX26_RS04075 Protein ID WP_283880494.1
Coordinates 845942..846340 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID C0PXM4
Locus tag QCX26_RS04070 Protein ID WP_000557545.1
Coordinates 845715..845942 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCX26_RS04040 (840770) 840770..841868 + 1099 WP_010989230.1 peptide chain release factor 2 -
QCX26_RS04045 (841878) 841878..843395 + 1518 WP_000003339.1 lysine--tRNA ligase -
QCX26_RS04050 (843471) 843471..844016 - 546 WP_000134000.1 isopentenyl-diphosphate Delta-isomerase -
QCX26_RS04055 (844281) 844281..845039 + 759 WP_000244328.1 amidase activator ActS -
QCX26_RS04065 (845294) 845294..845506 - 213 WP_063808845.1 hypothetical protein -
QCX26_RS04070 (845715) 845715..845942 + 228 WP_000557545.1 toxin-antitoxin system antitoxin VapB Antitoxin
QCX26_RS04075 (845942) 845942..846340 + 399 WP_283880494.1 tRNA(fMet)-specific endonuclease VapC Toxin
QCX26_RS04080 (847145) 847145..847681 + 537 WP_001038500.1 STM3031 family outer membrane protein -
QCX26_RS04085 (847728) 847728..848360 + 633 WP_283880498.1 YfdX family protein -
QCX26_RS04090 (849079) 849079..849660 + 582 WP_283880499.1 fimbrial protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 845294..854117 8823


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15018.38 Da        Isoelectric Point: 7.2927

>T276946 WP_283880494.1 NZ_CP122457:845942-846340 [Salmonella enterica subsp. enterica]
MLKFMLDTNTCIFTIKNKPEHIRERFNLNTSRMCISSITLMELIYGAEKSLAPEHNLAVVEGFISRLEVLDYDTQAAIHT
GQIRAELARKGTPVGPYDQMIAGHARSRGLVVVTNNLREFERIPGIRIEDWC

Download         Length: 399 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8500.48 Da        Isoelectric Point: 5.0053

>AT276946 WP_000557545.1 NZ_CP122457:845715-845942 [Salmonella enterica subsp. enterica]
MHTTLFFSNRTQAVRLPKSISFPDDVKHVEIIAVGRSRIITPVGESWDSWFDGEGASTDFMSTREQPAVQEREGF

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0R9MGW6

References