Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 835946..836606 Replicon chromosome
Accession NZ_CP122457
Organism Salmonella enterica subsp. enterica strain TZ282

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag QCX26_RS04015 Protein ID WP_000244756.1
Coordinates 836193..836606 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag QCX26_RS04010 Protein ID WP_000351186.1
Coordinates 835946..836212 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCX26_RS03990 (831875) 831875..833308 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
QCX26_RS03995 (833466) 833466..833777 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
QCX26_RS04000 (833941) 833941..834600 + 660 WP_079983857.1 hemolysin III family protein -
QCX26_RS04005 (834716) 834716..835696 - 981 WP_000874175.1 tRNA-modifying protein YgfZ -
QCX26_RS04010 (835946) 835946..836212 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
QCX26_RS04015 (836193) 836193..836606 + 414 WP_000244756.1 protein YgfX Toxin
QCX26_RS04020 (836659) 836659..837180 - 522 WP_001055885.1 flavodoxin FldB -
QCX26_RS04025 (837293) 837293..838189 + 897 WP_079983858.1 site-specific tyrosine recombinase XerD -
QCX26_RS04030 (838213) 838213..838926 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QCX26_RS04035 (838932) 838932..840665 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T276945 WP_000244756.1 NZ_CP122457:836193-836606 [Salmonella enterica subsp. enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT276945 WP_000351186.1 NZ_CP122457:835946-836212 [Salmonella enterica subsp. enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References