Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yfjZ/CbtA-CbeA
Location 5077467..5078189 Replicon chromosome
Accession NZ_CP122442
Organism Enterobacter ludwigii strain I9455333cz

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag QCL67_RS24795 Protein ID WP_085119314.1
Coordinates 5077869..5078189 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag QCL67_RS24790 Protein ID WP_085119315.1
Coordinates 5077467..5077802 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCL67_RS24775 (QCL67_24775) 5073528..5075261 + 1734 WP_085119320.1 ATP-binding protein -
QCL67_RS24780 (QCL67_24780) 5075593..5076492 - 900 WP_085119318.1 SMEK domain-containing protein -
QCL67_RS24785 (QCL67_24785) 5076974..5077453 + 480 WP_085119317.1 DNA repair protein RadC -
QCL67_RS24790 (QCL67_24790) 5077467..5077802 + 336 WP_085119315.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
QCL67_RS24795 (QCL67_24795) 5077869..5078189 + 321 WP_085119314.1 TA system toxin CbtA family protein Toxin
QCL67_RS24800 (QCL67_24800) 5078303..5079136 + 834 WP_085119312.1 DUF4942 domain-containing protein -
QCL67_RS24810 (QCL67_24810) 5079439..5079945 + 507 WP_025202984.1 G/U mismatch-specific DNA glycosylase -
QCL67_RS24815 (QCL67_24815) 5080030..5081877 - 1848 WP_020883616.1 RNA polymerase sigma factor RpoD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5049515..5079945 30430
- flank IS/Tn - - 5072269..5073249 980


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(7-105)

Antitoxin

Antitoxin CbeA

(8-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12118.67 Da        Isoelectric Point: 5.0486

>T276862 WP_085119314.1 NZ_CP122442:5077869-5078189 [Enterobacter ludwigii]
MQTTTVPATLPVSSRLSPVQVWQQLLTYLLEHHYGLTLNDTPFHDDASIEEHIEAGITLADAVNFLVERYELVRTDRKGF
TWQEQTPFLTATDFLRARRATGLMNT

Download         Length: 321 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12522.16 Da        Isoelectric Point: 6.0590

>AT276862 WP_085119315.1 NZ_CP122442:5077467-5077802 [Enterobacter ludwigii]
MNKDATQIWGLNRDITPCFGARLVQEGNRLHFLADRAGFNGSFSEMQARDLDEAFPHFVAHMELMLLSGELNPRYSHCVT
LYRNGLTCEADTLGSYGYVYIAIYPSNQVKA

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References