Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3826779..3827250 Replicon chromosome
Accession NZ_CP122442
Organism Enterobacter ludwigii strain I9455333cz

Toxin (Protein)


Gene name relE Uniprot ID A0A839BQT8
Locus tag QCL67_RS18780 Protein ID WP_020885403.1
Coordinates 3826779..3827018 (-) Length 80 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A839BTQ9
Locus tag QCL67_RS18785 Protein ID WP_020885404.1
Coordinates 3827008..3827250 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCL67_RS18765 (QCL67_18765) 3823049..3823621 + 573 WP_032681842.1 PTS sugar transporter subunit IIA -
QCL67_RS18770 (QCL67_18770) 3823989..3826127 + 2139 WP_182268150.1 anaerobic ribonucleoside-triphosphate reductase -
QCL67_RS18775 (QCL67_18775) 3826266..3826730 + 465 WP_020885402.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
QCL67_RS18780 (QCL67_18780) 3826779..3827018 - 240 WP_020885403.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QCL67_RS18785 (QCL67_18785) 3827008..3827250 - 243 WP_020885404.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QCL67_RS18790 (QCL67_18790) 3827328..3829238 - 1911 WP_020885405.1 PRD domain-containing protein -
QCL67_RS18795 (QCL67_18795) 3829258..3830394 - 1137 WP_020885406.1 lactonase family protein -
QCL67_RS18800 (QCL67_18800) 3830513..3831253 - 741 WP_014168382.1 KDGP aldolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-77)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 80 a.a.        Molecular weight: 9093.63 Da        Isoelectric Point: 9.9348

>T276861 WP_020885403.1 NZ_CP122442:c3827018-3826779 [Enterobacter ludwigii]
MTYELVFDPRAFKEWTRLGDTVKNQFKKKLANVLVNPRVESARLHGLPDCDKIKLRSQGYRLVYQVQDNVVTVCVIAIG

Download         Length: 240 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9085.49 Da        Isoelectric Point: 5.1088

>AT276861 WP_020885404.1 NZ_CP122442:c3827250-3827008 [Enterobacter ludwigii]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTVSDSEDELIQTVRERLANPQKGIKVRLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A839BQT8

Antitoxin

Source ID Structure
AlphaFold DB A0A839BTQ9

References