Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 594250..594989 Replicon chromosome
Accession NZ_CP122442
Organism Enterobacter ludwigii strain I9455333cz

Toxin (Protein)


Gene name tacT Uniprot ID A0A9E6WPH7
Locus tag QCL67_RS02850 Protein ID WP_013087269.1
Coordinates 594504..594989 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID A0A9E6WPN8
Locus tag QCL67_RS02845 Protein ID WP_007869691.1
Coordinates 594250..594516 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCL67_RS02820 (QCL67_02820) 589274..590194 - 921 WP_025203512.1 kdo(2)-lipid IV(A) palmitoleoyltransferase -
QCL67_RS02825 (QCL67_02825) 590478..590954 - 477 WP_047366497.1 WbuC family cupin fold metalloprotein -
QCL67_RS02830 (QCL67_02830) 591129..591797 + 669 WP_163304562.1 helix-turn-helix domain-containing protein -
QCL67_RS02835 (QCL67_02835) 592198..593178 - 981 WP_000019445.1 IS5-like element ISKpn26 family transposase -
QCL67_RS02840 (QCL67_02840) 593379..594076 + 698 WP_249420797.1 IS1 family transposase -
QCL67_RS02845 (QCL67_02845) 594250..594516 + 267 WP_007869691.1 DUF1778 domain-containing protein Antitoxin
QCL67_RS02850 (QCL67_02850) 594504..594989 + 486 WP_013087269.1 GNAT family N-acetyltransferase Toxin
QCL67_RS02855 (QCL67_02855) 595365..595844 + 480 WP_182268921.1 hypothetical protein -
QCL67_RS02860 (QCL67_02860) 595866..596669 + 804 WP_000619352.1 TIGR02391 family protein -
QCL67_RS02865 (QCL67_02865) 596690..597649 + 960 Protein_550 restriction endonuclease -
QCL67_RS02870 (QCL67_02870) 597715..598877 + 1163 WP_085947771.1 IS3-like element IS3 family transposase -
QCL67_RS02875 (QCL67_02875) 598969..599964 + 996 WP_249420798.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 592198..598877 6679


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-146)

Antitoxin

Vibrio phage ICP1, Orf50

(6-82)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17736.45 Da        Isoelectric Point: 9.5181

>T276854 WP_013087269.1 NZ_CP122442:594504-594989 [Enterobacter ludwigii]
VGRVTAPEPLSSSHQLAEFVSGEAVLDDWLKQRGLKNQALGAARTFVVCKRDTKQVVGFYSLATGSVNHVEAMGSLRRNM
PDPIPVIILARLAVDVSYRGQGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKNFYLHHGFKASQTQERTLFLKLP
Q

Download         Length: 486 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10080.46 Da        Isoelectric Point: 4.3837

>AT276854 WP_007869691.1 NZ_CP122442:594250-594516 [Enterobacter ludwigii]
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILDRRVFNFNDEQYAEFIDMLDAPVSDEAAIDKLL
ARKPQWDV

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References