Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 100829..101486 Replicon chromosome
Accession NZ_CP122442
Organism Enterobacter ludwigii strain I9455333cz

Toxin (Protein)


Gene name cptA Uniprot ID G8LDB6
Locus tag QCL67_RS00515 Protein ID WP_014171514.1
Coordinates 101076..101486 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag QCL67_RS00510 Protein ID WP_003863437.1
Coordinates 100829..101095 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCL67_RS00490 (QCL67_00490) 96238..97671 - 1434 WP_025203279.1 6-phospho-beta-glucosidase BglA -
QCL67_RS00495 (QCL67_00495) 97788..98519 - 732 WP_020883729.1 MurR/RpiR family transcriptional regulator -
QCL67_RS00500 (QCL67_00500) 98786..99445 + 660 WP_014171517.1 hemolysin III family protein -
QCL67_RS00505 (QCL67_00505) 99554..100534 - 981 WP_020883730.1 tRNA-modifying protein YgfZ -
QCL67_RS00510 (QCL67_00510) 100829..101095 + 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
QCL67_RS00515 (QCL67_00515) 101076..101486 + 411 WP_014171514.1 protein YgfX Toxin
QCL67_RS00520 (QCL67_00520) 101493..102014 - 522 WP_014171513.1 flavodoxin FldB -
QCL67_RS00525 (QCL67_00525) 102116..103012 + 897 WP_014171511.1 site-specific tyrosine recombinase XerD -
QCL67_RS00530 (QCL67_00530) 103036..103749 + 714 WP_020883731.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QCL67_RS00535 (QCL67_00535) 103755..105488 + 1734 WP_113656427.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16217.15 Da        Isoelectric Point: 11.5020

>T276853 WP_014171514.1 NZ_CP122442:101076-101486 [Enterobacter ludwigii]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRIHARQGEIKLLMDSRLRWQGK
EWEILGMPWMIASGMMLRLRSVDSGRRQHLWLAADSMDSAEWRDLRRMLLQQLTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT276853 WP_003863437.1 NZ_CP122442:100829-101095 [Enterobacter ludwigii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A839BUV6

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References