Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 5588288..5588955 Replicon chromosome
Accession NZ_CP122407
Organism Rugamonas sp. DEMB1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QC826_RS25780 Protein ID WP_279763028.1
Coordinates 5588539..5588955 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QC826_RS25775 Protein ID WP_279763027.1
Coordinates 5588288..5588542 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC826_RS25750 (QC826_25750) 5583381..5584958 - 1578 WP_279763023.1 carboxylesterase family protein -
QC826_RS25755 (QC826_25755) 5585241..5586140 + 900 WP_279763024.1 LytTR family DNA-binding domain-containing protein -
QC826_RS25765 (QC826_25765) 5587001..5587201 + 201 WP_279763025.1 hypothetical protein -
QC826_RS25770 (QC826_25770) 5587384..5587809 - 426 WP_279763026.1 SRPBCC family protein -
QC826_RS25775 (QC826_25775) 5588288..5588542 + 255 WP_279763027.1 plasmid stabilization protein Antitoxin
QC826_RS25780 (QC826_25780) 5588539..5588955 + 417 WP_279763028.1 type II toxin-antitoxin system VapC family toxin Toxin
QC826_RS25785 (QC826_25785) 5589150..5589965 + 816 WP_279763029.1 small-conductance mechanosensitive ion channel -
QC826_RS25790 (QC826_25790) 5590084..5590410 - 327 WP_279763030.1 helix-turn-helix domain-containing protein -
QC826_RS25795 (QC826_25795) 5590568..5591197 + 630 WP_279763031.1 glutathione transferase GstA -
QC826_RS25800 (QC826_25800) 5591304..5591840 - 537 WP_279763032.1 DUF2058 domain-containing protein -
QC826_RS25805 (QC826_25805) 5592139..5592852 + 714 WP_279763033.1 PEP-CTERM sorting domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14987.38 Da        Isoelectric Point: 9.8612

>T276852 WP_279763028.1 NZ_CP122407:5588539-5588955 [Rugamonas sp. DEMB1]
MIVLDTNVVSEAMKPEPHPAVRAWLNKQVAETLYLSSVTLAELLFGIRALPAGKRKDTLARTLDGLMVPFRDRVLPFDVD
AARHYADLAVAAKVAGRGFPTPDGYIAAIAVSRRFIVASRDTAPYQAAGVTVINPWQS

Download         Length: 417 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9212.47 Da        Isoelectric Point: 6.2235

>AT276852 WP_279763027.1 NZ_CP122407:5588288-5588542 [Rugamonas sp. DEMB1]
MAMLTVRNLPDEVHRALRARAAQHGHSTEAEVRAILSNAVKPEARLRMGDVLAALGREIGLTNEDVESLTQTRDRTPAEP
MGLE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References