Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ParST/RES-TIGR02293 |
| Location | 5348938..5349836 | Replicon | chromosome |
| Accession | NZ_CP122407 | ||
| Organism | Rugamonas sp. DEMB1 | ||
Toxin (Protein)
| Gene name | ParT | Uniprot ID | - |
| Locus tag | QC826_RS24640 | Protein ID | WP_279762866.1 |
| Coordinates | 5348938..5349408 (-) | Length | 157 a.a. |
Antitoxin (Protein)
| Gene name | ParS | Uniprot ID | - |
| Locus tag | QC826_RS24645 | Protein ID | WP_279762867.1 |
| Coordinates | 5349405..5349836 (-) | Length | 144 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QC826_RS24615 (QC826_24615) | 5344095..5344403 | - | 309 | WP_093389958.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| QC826_RS24620 (QC826_24620) | 5344375..5344656 | - | 282 | WP_139236673.1 | hypothetical protein | - |
| QC826_RS24625 (QC826_24625) | 5344764..5345585 | - | 822 | WP_245774392.1 | ZIP family metal transporter | - |
| QC826_RS24630 (QC826_24630) | 5345659..5348449 | - | 2791 | Protein_4835 | DNA polymerase I | - |
| QC826_RS24635 (QC826_24635) | 5348576..5348887 | - | 312 | WP_279762865.1 | cupin | - |
| QC826_RS24640 (QC826_24640) | 5348938..5349408 | - | 471 | WP_279762866.1 | RES family NAD+ phosphorylase | Toxin |
| QC826_RS24645 (QC826_24645) | 5349405..5349836 | - | 432 | WP_279762867.1 | DUF2384 domain-containing protein | Antitoxin |
| QC826_RS24650 (QC826_24650) | 5350109..5350513 | + | 405 | WP_279762868.1 | hypothetical protein | - |
| QC826_RS24655 (QC826_24655) | 5350587..5351543 | + | 957 | WP_279762869.1 | homoserine kinase | - |
| QC826_RS24660 (QC826_24660) | 5351543..5352322 | + | 780 | WP_279762870.1 | BPSS1780 family membrane protein | - |
| QC826_RS24665 (QC826_24665) | 5352468..5354777 | - | 2310 | WP_279762871.1 | UvrD-helicase domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 157 a.a. Molecular weight: 16951.50 Da Isoelectric Point: 10.6632
>T276851 WP_279762866.1 NZ_CP122407:c5349408-5348938 [Rugamonas sp. DEMB1]
MTVSAWRIAVEAPGYSASDLSGAGAKRSGGRWNARRTAMVYCSSNIALAMLETLSFVRTGSLPFNRFLVRIDIPDLVWGR
REVLAPVPGGWDAVPAGRASMAAGDAWAFSRRSALLLVPSVIVPEEFNILLNPTHSDAAAIAATTVRRWVYDPRFF
MTVSAWRIAVEAPGYSASDLSGAGAKRSGGRWNARRTAMVYCSSNIALAMLETLSFVRTGSLPFNRFLVRIDIPDLVWGR
REVLAPVPGGWDAVPAGRASMAAGDAWAFSRRSALLLVPSVIVPEEFNILLNPTHSDAAAIAATTVRRWVYDPRFF
Download Length: 471 bp
Antitoxin
Download Length: 144 a.a. Molecular weight: 15393.83 Da Isoelectric Point: 4.9209
>AT276851 WP_279762867.1 NZ_CP122407:c5349836-5349405 [Rugamonas sp. DEMB1]
VKIVDDNVYLMNAADRIELIRSGVPAAHLAVLSVKMGMPEGRLLALLGMSRATVSRKVREHQPLAPEESERVLGVESLIG
QVDAMVRESGEPVGFDAARWLADWLAMPVPALNGRTPASYLDTIEGQKLLSDLLAMAQSGAYA
VKIVDDNVYLMNAADRIELIRSGVPAAHLAVLSVKMGMPEGRLLALLGMSRATVSRKVREHQPLAPEESERVLGVESLIG
QVDAMVRESGEPVGFDAARWLADWLAMPVPALNGRTPASYLDTIEGQKLLSDLLAMAQSGAYA
Download Length: 432 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|