Detailed information of TA system TA276849

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): hicAB/HicB(antitoxin)
• Location: 4781289..4782000
• Replicon: chromosome
• Accession: NZ_CP122407
• Organism: Rugamonas sp. DEMB1

Toxin (Protein)

• Gene name: hicA
• Uniprot ID: -
• Locus tag: QC826_RS22005
• Protein ID: WP_279762446.1
• Coordinates: 4781289..4781468 (+)
• Length: 60 a.a.

Antitoxin (Protein)

• Gene name: hicB
• Uniprot ID: -
• Locus tag: QC826_RS22010
• Protein ID: WP_279762447.1
• Coordinates: 4781581..4782000 (+)
• Length: 140 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HicA mRNA interferase family (3-58)

Antitoxin

• HicB-like antitoxin of toxin-antitoxin system (4-65)

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6674.79 Da
• Isoelectric Point: 10.6654

>T276849 WP_279762446.1 NZ_CP122407:4781289-4781468 [Rugamonas sp. DEMB1]
MKYSEFRRWLEKQGAVFTPAKGSHHKVSLIGRSTVFPYHGAQEMGTGLVEKIKKDLGLK

Nucleotide

• Length: 180 bp

Antitoxin

Protein

• Length: 140 a.a.
• Molecular weight: 15352.66 Da
• Isoelectric Point: 4.9345

>AT276849 WP_279762447.1 NZ_CP122407:4781581-4782000 [Rugamonas sp. DEMB1]
MLNYPVTLVPDTNGTYLVGFPDFPEANSVGDNIEDALKNAVDALESALEIYFDERRPVPAPSAPEPGQHLVALPALETAK
VLLWNEMYAQKVRKADLARMLNVHTPQVDRLFDLKHSSKIEFVEQAAKVLGKTLVVGLK

Nucleotide

• Length: 420 bp