Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpB-mazE/PRK09812-MazE
Location 4302800..4303392 Replicon chromosome
Accession NZ_CP122407
Organism Rugamonas sp. DEMB1

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag QC826_RS19745 Protein ID WP_279762085.1
Coordinates 4302800..4303147 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QC826_RS19750 Protein ID WP_279762086.1
Coordinates 4303141..4303392 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC826_RS19715 (QC826_19715) 4297976..4298155 - 180 WP_279762080.1 hypothetical protein -
QC826_RS19720 (QC826_19720) 4298294..4298719 - 426 WP_279762081.1 cupin domain-containing protein -
QC826_RS19725 (QC826_19725) 4298798..4299625 - 828 WP_279762082.1 AraC family transcriptional regulator -
QC826_RS19730 (QC826_19730) 4299977..4300192 + 216 Protein_3877 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
QC826_RS19735 (QC826_19735) 4300360..4300752 + 393 WP_279762083.1 hypothetical protein -
QC826_RS19740 (QC826_19740) 4301372..4302640 + 1269 WP_279762084.1 hypothetical protein -
QC826_RS19745 (QC826_19745) 4302800..4303147 - 348 WP_279762085.1 type II toxin-antitoxin system ChpB family toxin Toxin
QC826_RS19750 (QC826_19750) 4303141..4303392 - 252 WP_279762086.1 PbsX family transcriptional regulator Antitoxin
QC826_RS19755 (QC826_19755) 4303605..4304948 - 1344 WP_279762087.1 HipA domain-containing protein -
QC826_RS19760 (QC826_19760) 4304995..4305411 - 417 WP_279762088.1 helix-turn-helix domain-containing protein -
QC826_RS19765 (QC826_19765) 4306421..4306756 - 336 WP_279762089.1 ATP-binding protein -
QC826_RS19770 (QC826_19770) 4306819..4307940 - 1122 WP_279762090.1 HNH endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 4111927..4372166 260239


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(9-113)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12196.95 Da        Isoelectric Point: 8.9519

>T276848 WP_279762085.1 NZ_CP122407:c4303147-4302800 [Rugamonas sp. DEMB1]
VVSRVKFGRGDIVMVNLDPTEGHEQRGMRPALVLSTSAFNALGVVLVAPITQGGDFSRHAGFAASLSGAGTKTQGVALVN
QVHMLDFEARKARRVETVPESVVDDALARLRAITD

Download         Length: 348 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8801.21 Da        Isoelectric Point: 4.8778

>AT276848 WP_279762086.1 NZ_CP122407:c4303392-4303141 [Rugamonas sp. DEMB1]
MELSIQKWGNSAAVRLPTELLGILKVTLGDKLSVNVQPGGVLLKAARPAYSLADLVAQCDPNAPEPADMAAWTSVAPMGR
ETW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References