Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 4279594..4280255 Replicon chromosome
Accession NZ_CP122407
Organism Rugamonas sp. DEMB1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QC826_RS19625 Protein ID WP_279762064.1
Coordinates 4279594..4280007 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QC826_RS19630 Protein ID WP_279762065.1
Coordinates 4280004..4280255 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC826_RS19590 (QC826_19590) 4275043..4275873 - 831 WP_279762057.1 baseplate J/gp47 family protein -
QC826_RS19595 (QC826_19595) 4275870..4276202 - 333 WP_279762058.1 GPW/gp25 family protein -
QC826_RS19600 (QC826_19600) 4276205..4276399 - 195 WP_279762059.1 hypothetical protein -
QC826_RS19605 (QC826_19605) 4276588..4277184 - 597 WP_279762060.1 phage baseplate assembly protein V -
QC826_RS19610 (QC826_19610) 4277194..4277727 - 534 WP_279762061.1 hypothetical protein -
QC826_RS19615 (QC826_19615) 4277952..4278653 - 702 WP_279762062.1 hypothetical protein -
QC826_RS19620 (QC826_19620) 4278821..4279501 + 681 WP_279762063.1 XRE family transcriptional regulator -
QC826_RS19625 (QC826_19625) 4279594..4280007 - 414 WP_279762064.1 type II toxin-antitoxin system VapC family toxin Toxin
QC826_RS19630 (QC826_19630) 4280004..4280255 - 252 WP_279762065.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QC826_RS19635 (QC826_19635) 4280361..4280555 - 195 WP_279762066.1 hypothetical protein -
QC826_RS19640 (QC826_19640) 4280609..4282540 - 1932 WP_279762067.1 EAL domain-containing protein -
QC826_RS19645 (QC826_19645) 4282539..4282730 + 192 WP_279762068.1 hypothetical protein -
QC826_RS19650 (QC826_19650) 4282755..4284206 - 1452 WP_279762069.1 ATPase domain-containing protein -
QC826_RS19655 (QC826_19655) 4284203..4284607 - 405 WP_279762070.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 4111927..4372166 260239


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-66)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15113.47 Da        Isoelectric Point: 7.0134

>T276847 WP_279762064.1 NZ_CP122407:c4280007-4279594 [Rugamonas sp. DEMB1]
MSYLLDTNVLSELRRKMPNSVVLDWMARRPAATLYLSVLTLGELRKGVEGVNDPIRRANLLDWLENELPAFFAGRILAVD
AQVADRWGRMVAAAGRPVPAIDSLIGATAAHYGLSLVTRNARDFTDLGLDVINPWTP

Download         Length: 414 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9610.86 Da        Isoelectric Point: 4.8481

>AT276847 WP_279762065.1 NZ_CP122407:c4280255-4280004 [Rugamonas sp. DEMB1]
MQTWQMQEAKARLSELVKLAQTEGPQDITLHGRSVAVVLSREAFERLSGSKQSLVEFMRQSPLYDLEEIEFERDRSTTRE
TPL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References