276845

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParE-CopA/RHH(antitoxin)
Location 3404450..3405019 Replicon chromosome
Accession NZ_CP122407
Organism Rugamonas sp. DEMB1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag QC826_RS15395 Protein ID WP_279766499.1
Coordinates 3404450..3404692 (-) Length 81 a.a.

Antitoxin (Protein)


Gene name copA Uniprot ID -
Locus tag QC826_RS15400 Protein ID WP_279761389.1
Coordinates 3404729..3405019 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC826_RS15370 (QC826_15370) 3400328..3400732 + 405 WP_279761379.1 hypothetical protein -
QC826_RS15375 (QC826_15375) 3400832..3401368 + 537 WP_279761381.1 DUF2262 domain-containing protein -
QC826_RS15380 (QC826_15380) 3401844..3402137 + 294 WP_279761383.1 hypothetical protein -
QC826_RS15385 (QC826_15385) 3402288..3402614 + 327 WP_279761385.1 hypothetical protein -
QC826_RS15390 (QC826_15390) 3403716..3404402 + 687 WP_279761387.1 L-2-amino-thiazoline-4-carboxylic acid hydrolase -
QC826_RS15395 (QC826_15395) 3404450..3404692 - 243 WP_279766499.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QC826_RS15400 (QC826_15400) 3404729..3405019 - 291 WP_279761389.1 CopG family transcriptional regulator Antitoxin
QC826_RS15405 (QC826_15405) 3405287..3405739 + 453 WP_279761390.1 GNAT family N-acetyltransferase -
QC826_RS15410 (QC826_15410) 3405761..3406300 + 540 WP_279761392.1 hypothetical protein -
QC826_RS15415 (QC826_15415) 3406360..3408426 - 2067 WP_279761394.1 HAMP domain-containing sensor histidine kinase -
QC826_RS15420 (QC826_15420) 3408563..3409882 - 1320 WP_279761396.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-78)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 81 a.a.        Molecular weight: 9049.42 Da        Isoelectric Point: 10.1805

>T276845 WP_279766499.1 NZ_CP122407:c3404692-3404450 [Rugamonas sp. DEMB1]
MREFLGAKKPAAAKRAAAAIVKSIQLLGQQPQIGRPIGDLDLAYRELPITFGNTEYIARYRYADDTVTILRIHHQREADR

Download         Length: 243 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10904.94 Da        Isoelectric Point: 4.4974

>AT276845 WP_279761389.1 NZ_CP122407:c3405019-3404729 [Rugamonas sp. DEMB1]
MASSSTSAIAFKFDQETQERVERFAEARQSTPHGVVSEAIHQYLDREEKREALRLDTLNAWTECETTGLHVNADEVSAWL
DSWGKEDELPAPKSHM

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References