Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2722683..2723233 Replicon chromosome
Accession NZ_CP122407
Organism Rugamonas sp. DEMB1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QC826_RS12350 Protein ID WP_279766459.1
Coordinates 2722958..2723233 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QC826_RS12345 Protein ID WP_279765881.1
Coordinates 2722683..2722958 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC826_RS12315 (QC826_12315) 2718742..2719374 + 633 WP_279765875.1 2OG-Fe(II) oxygenase -
QC826_RS12320 (QC826_12320) 2719553..2720161 + 609 WP_279765876.1 TetR/AcrR family transcriptional regulator -
QC826_RS12325 (QC826_12325) 2720242..2720667 + 426 WP_279765877.1 hypothetical protein -
QC826_RS12330 (QC826_12330) 2720672..2721295 - 624 WP_279765878.1 response regulator transcription factor -
QC826_RS12335 (QC826_12335) 2721322..2721696 - 375 WP_279765879.1 hypothetical protein -
QC826_RS12340 (QC826_12340) 2721865..2722557 + 693 WP_279765880.1 response regulator transcription factor -
QC826_RS12345 (QC826_12345) 2722683..2722958 + 276 WP_279765881.1 ribbon-helix-helix domain-containing protein Antitoxin
QC826_RS12350 (QC826_12350) 2722958..2723233 + 276 WP_279766459.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QC826_RS12355 (QC826_12355) 2723252..2726344 - 3093 WP_279765883.1 two-component regulator propeller domain-containing protein -
QC826_RS12360 (QC826_12360) 2726539..2727549 + 1011 WP_279765884.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10591.19 Da        Isoelectric Point: 9.6918

>T276844 WP_279766459.1 NZ_CP122407:2722958-2723233 [Rugamonas sp. DEMB1]
MDLRWTSKALSDLIRLHEFLATVNKPAAARAVQSLTAAAASLLANPRIGERLEEFDPRDIRRILVGRYELRYEIEASTIY
LLRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10040.41 Da        Isoelectric Point: 5.6786

>AT276844 WP_279765881.1 NZ_CP122407:2722683-2722958 [Rugamonas sp. DEMB1]
MAQTETKVITAHIPLPLADKVDQLASRLERSRGWIVKQALSAWVDQEEERSRLTREAMADVAAGRVIDHQSVQAWADSLG
TDRPLAAPVLP

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References