Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-copA/RHH(antitoxin)
Location 2298746..2299313 Replicon chromosome
Accession NZ_CP122407
Organism Rugamonas sp. DEMB1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QC826_RS10580 Protein ID WP_279765564.1
Coordinates 2299146..2299313 (+) Length 56 a.a.

Antitoxin (Protein)


Gene name copA Uniprot ID -
Locus tag QC826_RS10570 Protein ID WP_279765563.1
Coordinates 2298746..2299036 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC826_RS10550 (QC826_10550) 2294281..2296017 - 1737 WP_279766442.1 TonB-dependent receptor -
QC826_RS10555 (QC826_10555) 2296118..2296213 - 96 Protein_2061 hypothetical protein -
QC826_RS10560 (QC826_10560) 2296887..2297900 - 1014 WP_279765561.1 FecR domain-containing protein -
QC826_RS10565 (QC826_10565) 2297891..2298418 - 528 WP_279765562.1 sigma-70 family RNA polymerase sigma factor -
QC826_RS10570 (QC826_10570) 2298746..2299036 + 291 WP_279765563.1 CopG family ribbon-helix-helix protein Antitoxin
QC826_RS10575 (QC826_10575) 2299024..2299089 + 66 Protein_2065 hypothetical protein -
QC826_RS10580 (QC826_10580) 2299146..2299313 + 168 WP_279765564.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QC826_RS10585 (QC826_10585) 2299475..2299615 - 141 WP_279765566.1 hypothetical protein -
QC826_RS10590 (QC826_10590) 2299902..2300648 - 747 WP_279765567.1 FHA domain-containing protein -
QC826_RS10595 (QC826_10595) 2300660..2301421 - 762 WP_279765569.1 hypothetical protein -
QC826_RS10600 (QC826_10600) 2301594..2302589 - 996 WP_279765570.1 protein phosphatase 2C domain-containing protein -
QC826_RS10605 (QC826_10605) 2302678..2303208 - 531 WP_279765571.1 SH3 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-53)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-46)


Sequences

Toxin        


Download         Length: 56 a.a.        Molecular weight: 6206.99 Da        Isoelectric Point: 4.8435

>T276843 WP_279765564.1 NZ_CP122407:2299146-2299313 [Rugamonas sp. DEMB1]
VLGHQPQIGRPIDGMAEVYREWQIDFGDSGYVVRYRTAPDAVIVLAVRYQKEAGD

Download         Length: 168 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11194.53 Da        Isoelectric Point: 5.5799

>AT276843 WP_279765563.1 NZ_CP122407:2298746-2299036 [Rugamonas sp. DEMB1]
MTAAVARPMSVKLDPDTRARLEHLAESRRRTPHWMLREAVAQYLEREEKRESFRHDTLKAWEEYRTTGLHVTADEADAWL
AQLAEGNDIEPPECHV

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References