Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1810507..1811258 Replicon chromosome
Accession NZ_CP122407
Organism Rugamonas sp. DEMB1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QC826_RS08320 Protein ID WP_279765163.1
Coordinates 1810983..1811258 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QC826_RS08315 Protein ID WP_279765162.1
Coordinates 1810507..1810983 (+) Length 159 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC826_RS08290 (QC826_08290) 1805870..1806484 + 615 WP_093390674.1 TetR/AcrR family transcriptional regulator -
QC826_RS08295 (QC826_08295) 1806663..1807208 + 546 WP_279765159.1 hypothetical protein -
QC826_RS08300 (QC826_08300) 1807292..1807636 - 345 WP_279765160.1 hypothetical protein -
QC826_RS08305 (QC826_08305) 1807750..1809311 + 1562 WP_279764258.1 IS3 family transposase -
QC826_RS08310 (QC826_08310) 1809652..1810236 - 585 WP_279765161.1 hypothetical protein -
QC826_RS08315 (QC826_08315) 1810507..1810983 + 477 WP_279765162.1 CopG family ribbon-helix-helix protein Antitoxin
QC826_RS08320 (QC826_08320) 1810983..1811258 + 276 WP_279765163.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QC826_RS08325 (QC826_08325) 1811295..1812278 - 984 WP_279765164.1 FHA domain-containing protein -
QC826_RS08330 (QC826_08330) 1812275..1813645 - 1371 WP_279765165.1 serine protease -
QC826_RS08335 (QC826_08335) 1813682..1814335 - 654 WP_099416345.1 GTP cyclohydrolase II -
QC826_RS08340 (QC826_08340) 1814510..1815211 - 702 WP_279765166.1 pirin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(76-112)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10722.32 Da        Isoelectric Point: 9.6533

>T276841 WP_279765163.1 NZ_CP122407:1810983-1811258 [Rugamonas sp. DEMB1]
VELRWTKKSLSDLTRLHEFLAAVNEPAAARTVQSLTAAAASLLENPRIGERLEEFEPREIRRILVGRYELRYEIKASTIY
IMRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 159 a.a.        Molecular weight: 17610.41 Da        Isoelectric Point: 4.6552

>AT276841 WP_279765162.1 NZ_CP122407:1810507-1810983 [Rugamonas sp. DEMB1]
VKIAPPLRRRVQGNALSRRYACENYHPEYSLDTDTDTDTDTDTDTDTDTDNDNALAHFEKANLKGSFMAHTETKVFTAHV
PVALAEKVDQLASRLERSRGWIVKQALSAWVDLEEERSRLTREAMADVEAGHVIDHQSVQAWADSLGTENPLPAPVVP

Download         Length: 477 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References