Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parE_1-relB/RelE(toxin)
Location 738032..738567 Replicon chromosome
Accession NZ_CP122407
Organism Rugamonas sp. DEMB1

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag QC826_RS03485 Protein ID WP_279764412.1
Coordinates 738280..738567 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QC826_RS03480 Protein ID WP_279764411.1
Coordinates 738032..738232 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC826_RS03455 (QC826_03455) 733891..735138 + 1248 WP_279764407.1 hypothetical protein -
QC826_RS03460 (QC826_03460) 735172..735441 + 270 WP_093389697.1 hypothetical protein -
QC826_RS03465 (QC826_03465) 735955..736080 + 126 WP_279764408.1 hypothetical protein -
QC826_RS03470 (QC826_03470) 736114..736392 + 279 WP_279764409.1 hypothetical protein -
QC826_RS03475 (QC826_03475) 737363..737857 + 495 WP_279764410.1 site-specific integrase -
QC826_RS03480 (QC826_03480) 738032..738232 + 201 WP_279764411.1 hypothetical protein Antitoxin
QC826_RS03485 (QC826_03485) 738280..738567 + 288 WP_279764412.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QC826_RS03490 (QC826_03490) 738702..738956 - 255 WP_279764413.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
QC826_RS03495 (QC826_03495) 739144..739533 + 390 WP_279764414.1 DUF5710 domain-containing protein -
QC826_RS03500 (QC826_03500) 739948..740355 - 408 WP_279764415.1 hypothetical protein -
QC826_RS03505 (QC826_03505) 740641..741234 + 594 WP_279764416.1 hypothetical protein -
QC826_RS03510 (QC826_03510) 741250..741930 + 681 WP_279764417.1 hypothetical protein -
QC826_RS03515 (QC826_03515) 741963..743162 + 1200 WP_279764418.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10690.40 Da        Isoelectric Point: 9.3693

>T276840 WP_279764412.1 NZ_CP122407:738280-738567 [Rugamonas sp. DEMB1]
MLPVQWLAKANINLATIITYIAERNDVAASELQNDIERAVSQLPQHPYLYRPGRVAGTREIVVHANYVVVYRVLPTVIEI
VAVLHTRQQYPAAAK

Download         Length: 288 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7300.05 Da        Isoelectric Point: 4.6472

>AT276840 WP_279764411.1 NZ_CP122407:738032-738232 [Rugamonas sp. DEMB1]
MNTVLSPIESEFATAEEAAAYDRWFRAQVQESIDDSRPSIPHDQVMAEMRAIIASKRKNAGSNSSS

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References