Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4016312..4016969 Replicon chromosome
Accession NZ_CP122401
Organism Enterobacter roggenkampii strain EOBSR_19

Toxin (Protein)


Gene name cptA Uniprot ID W7P4L3
Locus tag QCD67_RS19495 Protein ID WP_023326024.1
Coordinates 4016559..4016969 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID W7NX65
Locus tag QCD67_RS19490 Protein ID WP_006178375.1
Coordinates 4016312..4016578 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCD67_RS19470 (QCD67_19470) 4011746..4013179 - 1434 WP_023294510.1 6-phospho-beta-glucosidase BglA -
QCD67_RS19475 (QCD67_19475) 4013296..4014027 - 732 WP_008499714.1 MurR/RpiR family transcriptional regulator -
QCD67_RS19480 (QCD67_19480) 4014293..4014952 + 660 WP_021242052.1 hemolysin III family protein -
QCD67_RS19485 (QCD67_19485) 4015037..4016017 - 981 WP_248275221.1 tRNA-modifying protein YgfZ -
QCD67_RS19490 (QCD67_19490) 4016312..4016578 + 267 WP_006178375.1 FAD assembly factor SdhE Antitoxin
QCD67_RS19495 (QCD67_19495) 4016559..4016969 + 411 WP_023326024.1 protein YgfX Toxin
QCD67_RS19500 (QCD67_19500) 4016976..4017497 - 522 WP_045909912.1 flavodoxin FldB -
QCD67_RS19505 (QCD67_19505) 4017599..4018495 + 897 WP_008499709.1 site-specific tyrosine recombinase XerD -
QCD67_RS19510 (QCD67_19510) 4018524..4019237 + 714 WP_008499708.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QCD67_RS19515 (QCD67_19515) 4019243..4020976 + 1734 WP_279794314.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16063.06 Da        Isoelectric Point: 10.9468

>T276838 WP_023326024.1 NZ_CP122401:4016559-4016969 [Enterobacter roggenkampii]
VVLWQSDLRVSWRSQWMSLLLHGLVAAIVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNCGMMLRLRKVDGGRCQHLWLAADSMDAAEWRDLRRMLLQQTTQG

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10569.05 Da        Isoelectric Point: 5.1340

>AT276838 WP_006178375.1 NZ_CP122401:4016312-4016578 [Enterobacter roggenkampii]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB W7P4L3

Antitoxin

Source ID Structure
AlphaFold DB W7NX65

References