Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 2919024..2919620 Replicon chromosome
Accession NZ_CP122401
Organism Enterobacter roggenkampii strain EOBSR_19

Toxin (Protein)


Gene name PumA Uniprot ID A0A0F1DED9
Locus tag QCD67_RS14285 Protein ID WP_023293553.1
Coordinates 2919024..2919326 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID W7P674
Locus tag QCD67_RS14290 Protein ID WP_021242718.1
Coordinates 2919333..2919620 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCD67_RS14265 (QCD67_14265) 2915006..2916580 + 1575 WP_008503417.1 RNA repair transcriptional activator RtcR -
QCD67_RS14270 (QCD67_14270) 2916686..2917630 + 945 WP_023293551.1 ketopantoate/pantoate/pantothenate transporter PanS -
QCD67_RS14275 (QCD67_14275) 2917681..2917953 + 273 WP_014830263.1 DUF3811 domain-containing protein -
QCD67_RS14280 (QCD67_14280) 2917954..2918826 - 873 WP_008503414.1 23S rRNA pseudouridine(2604) synthase RluF -
QCD67_RS14285 (QCD67_14285) 2919024..2919326 + 303 WP_023293553.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QCD67_RS14290 (QCD67_14290) 2919333..2919620 + 288 WP_021242718.1 putative addiction module antidote protein Antitoxin
QCD67_RS14295 (QCD67_14295) 2919617..2921248 - 1632 WP_008503411.1 Na/Pi cotransporter family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-93)

Antitoxin

Uncharacterized protein HI1420

(3-89)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11459.24 Da        Isoelectric Point: 10.1771

>T276837 WP_023293553.1 NZ_CP122401:2919024-2919326 [Enterobacter roggenkampii]
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDVKPVGEGISELRIHFGPGYRIYFKDQGNYIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE

Download         Length: 303 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10156.57 Da        Isoelectric Point: 6.4596

>AT276837 WP_021242718.1 NZ_CP122401:2919333-2919620 [Enterobacter roggenkampii]
MHKLTPYDPANALVDDEEIAVFIADALETGDSTYIAKALGVVARAKGMSNISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGFGLTLKHAGD

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0F1DED9

Antitoxin

Source ID Structure
AlphaFold DB W7P674

References