Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2070008..2070153 Replicon chromosome
Accession NZ_CP122389
Organism Klebsiella pneumoniae strain KP9650

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2070044..2070146 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2070008..2070153 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCB43_RS10105 (QCB43_10105) 2065138..2067198 + 2061 WP_032446301.1 oligopeptidase B -
QCB43_RS10110 (QCB43_10110) 2067202..2067861 - 660 WP_002911407.1 exodeoxyribonuclease X -
QCB43_RS10115 (QCB43_10115) 2067940..2068170 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QCB43_RS10120 (QCB43_10120) 2068283..2068657 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QCB43_RS10125 (QCB43_10125) 2068661..2069530 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
QCB43_RS10130 (QCB43_10130) 2069547..2069885 + 339 WP_023301072.1 YebY family protein -
- 2070008..2070153 - 146 - - Antitoxin
- 2070044..2070146 + 103 - - Toxin
QCB43_RS10135 (QCB43_10135) 2070521..2070664 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QCB43_RS10140 (QCB43_10140) 2070769..2071737 - 969 WP_004151446.1 VirK/YbjX family protein -
QCB43_RS10145 (QCB43_10145) 2071894..2072547 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QCB43_RS10150 (QCB43_10150) 2072544..2072735 - 192 WP_002911395.1 YebW family protein -
QCB43_RS10155 (QCB43_10155) 2072833..2073072 - 240 WP_002911393.1 YebV family protein -
QCB43_RS10160 (QCB43_10160) 2073188..2074621 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T276816 NZ_CP122389:2070044-2070146 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT276816 NZ_CP122389:c2070153-2070008 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References