276806

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2131816..2133377 Replicon chromosome
Accession NZ_CP122328
Organism Pantoea agglomerans pv. betae strain 4188

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag A7P61_RS14230 Protein ID WP_064704321.1
Coordinates 2132064..2133377 (+) Length 438 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag A7P61_RS14225 Protein ID WP_022625644.1
Coordinates 2131816..2132064 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7P61_RS14205 (A7P61_14205) 2127063..2129288 + 2226 WP_064704319.1 iron ABC transporter permease -
A7P61_RS14210 (A7P61_14210) 2129285..2130346 + 1062 WP_039386572.1 ABC transporter ATP-binding protein -
A7P61_RS14215 (A7P61_14215) 2130370..2131164 + 795 WP_064704320.1 inositol monophosphatase family protein -
A7P61_RS14220 (A7P61_14220) 2131198..2131635 - 438 WP_031592296.1 GNAT family N-acetyltransferase -
A7P61_RS14225 (A7P61_14225) 2131816..2132064 + 249 WP_022625644.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
A7P61_RS14230 (A7P61_14230) 2132064..2133377 + 1314 WP_064704321.1 type II toxin-antitoxin system HipA family toxin Toxin
A7P61_RS14235 (A7P61_14235) 2133515..2133688 + 174 WP_230873490.1 type II toxin-antitoxin system MqsA family antitoxin -
A7P61_RS14240 (A7P61_14240) 2134015..2135397 + 1383 WP_064704322.1 M24 family metallopeptidase -
A7P61_RS14245 (A7P61_14245) 2135512..2137557 + 2046 WP_064704323.1 FUSC family protein -
A7P61_RS14250 (A7P61_14250) 2137953..2138288 - 336 WP_039386593.1 gamma-glutamylcyclotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(149-402)

Antitoxin

Cro/C1-type helix-turn-helix domain

(9-54)


Sequences

Toxin        


Download         Length: 438 a.a.        Molecular weight: 49175.78 Da        Isoelectric Point: 8.4280

>T276806 WP_064704321.1 NZ_CP122328:2132064-2133377 [Pantoea agglomerans pv. betae]
MQRLIAWMNGERVGVLTRQRNGAHEFQYDTAWLSNPLSRPLSLSMPLQVKAITSHAVINFFDNLLPDSPLIRDRIVARYQ
IKSRQPFDLLQEVGRDSVGATMLLPPDMPLPALQARYEVLDETRLESVLSAYQSDIPLGMLREETDFRISVAGAQEKTAL
LLTDEGWSIPAGATPTSHIIKLPIGEIKQPAATLDMRESVENEYLCLALARALGIDVPQATIIRAGQMRALAVERFDRRW
SRDKTRLIRLPQEDFCQALGLPSSTKYESDGGPGIAEIMQILMGSSNAIEDRYRFMMFQVFQWLIGATDGHAKNFSLFIE
RGGSYRLTPFYDVISAYPVLGGTGLNKRALKLAMGLRATKGKKTEIDKIFPRHFIATAKSVSFDRESLQQIFDFFIKAFP
QAVVSVRDALPPDFPQHIADAIFSHSLIMLERLRHKE

Download         Length: 1314 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9363.61 Da        Isoelectric Point: 5.0775

>AT276806 WP_022625644.1 NZ_CP122328:2131816-2132064 [Pantoea agglomerans pv. betae]
MIYSPLQLANRLKLIRQRNGWTQSELAKKVGLKQATISHFENAPDSTSLATLFKLLQSLELSLEVQEKEEASAPQLHDED
EW

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References