Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 31098..31624 Replicon plasmid pPAB03
Accession NZ_CP122326
Organism Pantoea agglomerans pv. betae strain 4188

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A7P61_RS02715 Protein ID WP_031593074.1
Coordinates 31098..31385 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A7P61_RS02720 Protein ID WP_064703129.1
Coordinates 31385..31624 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7P61_RS02690 (A7P61_02690) 26998..28023 - 1026 WP_031593079.1 alpha/beta hydrolase -
A7P61_RS02695 (A7P61_02695) 28092..29216 - 1125 WP_081273776.1 MFS transporter -
A7P61_RS02700 (A7P61_02700) 29419..30315 + 897 WP_064703127.1 LysR family transcriptional regulator -
A7P61_RS02705 (A7P61_02705) 30379..30555 - 177 WP_074399946.1 general stress protein -
A7P61_RS02710 (A7P61_02710) 30757..31053 + 297 WP_064703128.1 hypothetical protein -
A7P61_RS02715 (A7P61_02715) 31098..31385 - 288 WP_031593074.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A7P61_RS02720 (A7P61_02720) 31385..31624 - 240 WP_064703129.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
A7P61_RS02725 (A7P61_02725) 31965..33938 + 1974 WP_064703130.1 methyl-accepting chemotaxis protein -
A7P61_RS02730 (A7P61_02730) 34043..35059 + 1017 WP_039387390.1 NAD(P)-dependent alcohol dehydrogenase -
A7P61_RS02735 (A7P61_02735) 35109..35777 - 669 WP_064703131.1 DUF2268 domain-containing putative Zn-dependent protease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..178621 178621


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-78)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11039.97 Da        Isoelectric Point: 10.2591

>T276799 WP_031593074.1 NZ_CP122326:c31385-31098 [Pantoea agglomerans pv. betae]
MPWQLECDQRALKEWRKLGPTVREQLKKKLAECLESPRIEANKLSRMPDCYKIKLKSSGYRLAYQVIDDRVVVFVVAVGK
RERSEVCSAASRRLS

Download         Length: 288 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8911.29 Da        Isoelectric Point: 5.1070

>AT276799 WP_064703129.1 NZ_CP122326:c31624-31385 [Pantoea agglomerans pv. betae]
VGSISIRIDDDLKRRSFAALKKMGVTPSDALRLMLAYIADNERLPFKQTSLSDEDAALVDIVEERLRNPEPVRITLDKL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References