Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 315074..315984 | Replicon | plasmid pPAB02 |
| Accession | NZ_CP122325 | ||
| Organism | Pantoea agglomerans pv. betae strain 4188 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | A7P61_RS01460 | Protein ID | WP_064703870.1 |
| Coordinates | 315074..315544 (-) | Length | 157 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | A7P61_RS01465 | Protein ID | WP_064703869.1 |
| Coordinates | 315541..315984 (-) | Length | 148 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A7P61_RS01450 (A7P61_01450) | 311153..313882 | + | 2730 | WP_064703872.1 | cation-transporting P-type ATPase | - |
| A7P61_RS01455 (A7P61_01455) | 313871..314902 | - | 1032 | WP_064703871.1 | AI-2E family transporter | - |
| A7P61_RS01460 (A7P61_01460) | 315074..315544 | - | 471 | WP_064703870.1 | RES family NAD+ phosphorylase | Toxin |
| A7P61_RS01465 (A7P61_01465) | 315541..315984 | - | 444 | WP_064703869.1 | DUF2384 domain-containing protein | Antitoxin |
| A7P61_RS01470 (A7P61_01470) | 316129..316386 | + | 258 | Protein_293 | aldo/keto reductase | - |
| A7P61_RS01475 (A7P61_01475) | 316421..316838 | - | 418 | Protein_294 | LysR substrate-binding domain-containing protein | - |
| A7P61_RS01480 (A7P61_01480) | 317052..317666 | + | 615 | WP_064703867.1 | TetR/AcrR family transcriptional regulator | - |
| A7P61_RS01485 (A7P61_01485) | 317717..318616 | + | 900 | WP_064703866.1 | alpha/beta hydrolase | - |
| A7P61_RS01490 (A7P61_01490) | 318858..320045 | + | 1188 | WP_064703865.1 | M20 family metallopeptidase | - |
| A7P61_RS01495 (A7P61_01495) | 320067..320915 | + | 849 | WP_022624593.1 | transporter substrate-binding domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | iroN | 1..541337 | 541337 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 157 a.a. Molecular weight: 17440.86 Da Isoelectric Point: 4.7699
>T276798 WP_064703870.1 NZ_CP122325:c315544-315074 [Pantoea agglomerans pv. betae]
MILYRLTKTKYLSTAWTGFGAKEAGGRWNSIGISMVYVSETASLTLLETLVHLHSAHILDAFTLLRIDVPDALIQTADIT
ELPANWADEDAPAELADYGDAWCSACDAVALRVPSALSPVEYNYLLNPEHPDFFRIVQQAEAIPFRFDRRLKADRK
MILYRLTKTKYLSTAWTGFGAKEAGGRWNSIGISMVYVSETASLTLLETLVHLHSAHILDAFTLLRIDVPDALIQTADIT
ELPANWADEDAPAELADYGDAWCSACDAVALRVPSALSPVEYNYLLNPEHPDFFRIVQQAEAIPFRFDRRLKADRK
Download Length: 471 bp
Antitoxin
Download Length: 148 a.a. Molecular weight: 16463.84 Da Isoelectric Point: 9.9250
>AT276798 WP_064703869.1 NZ_CP122325:c315984-315541 [Pantoea agglomerans pv. betae]
MKTFSFSANKTRAPRLWQAAGLNNADGVALLGQINEGLDGNVAHLIVNWAKITQNDLRKMSGIPSTTFSRSVKAKFSAEQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKMPAELMASETGAYEVMKLITRLEHGVYS
MKTFSFSANKTRAPRLWQAAGLNNADGVALLGQINEGLDGNVAHLIVNWAKITQNDLRKMSGIPSTTFSRSVKAKFSAEQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKMPAELMASETGAYEVMKLITRLEHGVYS
Download Length: 444 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|