Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 991377..991648 Replicon chromosome
Accession NZ_CP122318
Organism Escherichia coli strain HT873X1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 991507..991610 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 991377..991648 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCG45_RS04755 987932..988594 - 663 WP_000944256.1 exodeoxyribonuclease X -
QCG45_RS04760 988618..989274 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
QCG45_RS04765 989376..989606 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QCG45_RS04770 989745..990119 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QCG45_RS04775 990123..990995 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
QCG45_RS04780 991008..991349 + 342 WP_000976476.1 YebY family protein -
- 991377..991648 - 272 - - Antitoxin
- 991507..991610 + 104 - - Toxin
QCG45_RS04785 991745..992401 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
QCG45_RS04790 992402..992593 - 192 WP_000457842.1 YebW family protein -
QCG45_RS04795 992698..992934 - 237 WP_001295499.1 YebV family protein -
QCG45_RS04800 993052..994491 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T276725 NZ_CP122318:991507-991610 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT276725 NZ_CP122318:c991648-991377 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References