Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 454577..454848 Replicon chromosome
Accession NZ_CP122317
Organism Escherichia coli strain HT-948

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 454615..454718 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 454577..454848 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCG49_RS02260 451734..453173 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
QCG49_RS02265 453291..453527 + 237 WP_001295499.1 YebV family protein -
QCG49_RS02270 453632..453823 + 192 WP_000457842.1 YebW family protein -
QCG49_RS02275 453824..454480 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 454577..454848 + 272 - - Antitoxin
- 454615..454718 - 104 - - Toxin
QCG49_RS02280 454876..455217 - 342 WP_000976476.1 YebY family protein -
QCG49_RS02285 455230..456102 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
QCG49_RS02290 456106..456480 - 375 WP_000168747.1 CopC domain-containing protein YobA -
QCG49_RS02295 456619..456849 + 231 WP_000916763.1 DNA polymerase III subunit theta -
QCG49_RS02300 456951..457607 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
QCG49_RS02305 457631..458293 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T276689 NZ_CP122317:c454718-454615 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT276689 NZ_CP122317:454577-454848 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References