276599

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 2995874..2996790 Replicon chromosome
Accession NZ_CP121861
Organism Bacillus stercoris strain Mal05

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag QA442_RS15570 Protein ID WP_095431469.1
Coordinates 2995874..2996620 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID G4NV07
Locus tag QA442_RS15575 Protein ID WP_003239095.1
Coordinates 2996620..2996790 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA442_RS15545 (2990956) 2990956..2991102 - 147 WP_141237713.1 hypothetical protein -
QA442_RS15550 (2991202) 2991202..2992152 - 951 WP_095431468.1 ring-cleaving dioxygenase -
QA442_RS15555 (2992540) 2992540..2993856 + 1317 WP_014663668.1 serine/threonine exchanger -
QA442_RS15560 (2994133) 2994133..2994750 + 618 WP_003218470.1 DUF47 domain-containing protein -
QA442_RS15565 (2994763) 2994763..2995764 + 1002 WP_014663667.1 inorganic phosphate transporter -
QA442_RS15570 (2995874) 2995874..2996620 + 747 WP_095431469.1 toxin-antitoxin-antitoxin system toxin SpoIISA Toxin
QA442_RS15575 (2996620) 2996620..2996790 + 171 WP_003239095.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISB Antitoxin
QA442_RS15580 (2996876) 2996876..2997013 + 138 WP_136654612.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISC -
QA442_RS15585 (2997051) 2997051..2997944 - 894 WP_095431470.1 N-acetylmuramoyl-L-alanine amidase -
QA442_RS15590 (2997957) 2997957..2998220 - 264 WP_003232653.1 phage holin -
QA442_RS15595 (2998233) 2998233..2998502 - 270 WP_003232655.1 hemolysin XhlA family protein -
QA442_RS15600 (2998555) 2998555..2999394 - 840 WP_095431471.1 phage portal protein -
QA442_RS15605 (2999439) 2999439..2999603 - 165 WP_040083360.1 XkdX family protein -
QA442_RS15610 (2999600) 2999600..2999929 - 330 WP_040083361.1 XkdW family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29070.57 Da        Isoelectric Point: 4.6145

>T276599 WP_095431469.1 NZ_CP121861:2995874-2996620 [Bacillus stercoris]
MVLFFQIMVWCIVAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYEPTSLFTHWDRYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASL
CQYSTQADKDRLTEHMDDPADVQTRLDRKDVYYDQYGKMVLIPFTIETKNYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6555.59 Da        Isoelectric Point: 10.8401

>AT276599 WP_003239095.1 NZ_CP121861:2996620-2996790 [Bacillus stercoris]
MERAFQNGCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB G4NV07

References