Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 4377112..4378685 Replicon chromosome
Accession NZ_CP121851
Organism Aeromonas veronii strain ANYA 14022

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag QBS11_RS20430 Protein ID WP_279491488.1
Coordinates 4377112..4378431 (-) Length 440 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag QBS11_RS20435 Protein ID WP_017410478.1
Coordinates 4378431..4378685 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QBS11_RS20415 4373030..4373794 + 765 WP_279491486.1 ATP-binding cassette domain-containing protein -
QBS11_RS20420 4373828..4374712 + 885 WP_058059808.1 ABC transporter substrate-binding protein -
QBS11_RS20425 4374709..4376691 + 1983 WP_279491487.1 Fe(3+)-hydroxamate ABC transporter permease FhuB -
QBS11_RS20430 4377112..4378431 - 1320 WP_279491488.1 type II toxin-antitoxin system HipA family toxin Toxin
QBS11_RS20435 4378431..4378685 - 255 WP_017410478.1 helix-turn-helix domain-containing protein Antitoxin
QBS11_RS20440 4379224..4379841 + 618 WP_031227892.1 recombinase family protein -
QBS11_RS20445 4379838..4380161 - 324 WP_101778626.1 hypothetical protein -
QBS11_RS20450 4380900..4383365 + 2466 WP_279491489.1 DEAD/DEAH box helicase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(4-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(13-65)


Sequences

Toxin        


Download         Length: 440 a.a.        Molecular weight: 49628.69 Da        Isoelectric Point: 7.0152

>T276587 WP_279491488.1 NZ_CP121851:c4378431-4377112 [Aeromonas veronii]
MANLAVYMNGYRVGTFTKTTSGAHQFQYHESWLAQPGSRPISLSMPLRHQAYRGDETYNFFDNLLPDNTEVRNRVVARYQ
AASTQPFDLLSCIGQDSVGALQLVTEGHDVLDVRRIDYKALSDDELEQILTSYKSGIPLGMVREQEEFRISIAGAQEKTA
LLYIDGRWYLPLKATPTTHIIKLPIGKIESHSYSIDLSQSVENEYICTLIAKEFGLPVPHCFMMQVGQVKALAVERFDRR
YAADRSWIMRLPQEDFCQVLNVPSARKYESHGGPGITDIMKTLLGSATPEQDRYLFMKSQVLFWLLAATDGHAKNFSVFI
EPEGRFRLTPFYDILSVYPVFGGRGLNRRDAKLAMGLASSKGRKYAIEQIFPRHFFQTAKTVGFERSAMEEILTELANAV
DDVIERVTRQLPADFPDAISSTILEGLKARSARLIKGWD

Download         Length: 1320 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9293.62 Da        Isoelectric Point: 7.9834

>AT276587 WP_017410478.1 NZ_CP121851:c4378685-4378431 [Aeromonas veronii]
MKVTSAKQLSACIKDARLSQKLSQGKVAEKVGIRQDTVSSFELNPESTKLETLFKILAALELSVDIKPRNESSESPASGW
KEEW

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References