Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 3844913..3846321 Replicon chromosome
Accession NZ_CP121845
Organism Aeromonas veronii strain ANYA 15694

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag QBS37_RS18755 Protein ID WP_279475526.1
Coordinates 3845167..3846321 (+) Length 385 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag QBS37_RS18750 Protein ID WP_005329233.1
Coordinates 3844913..3845167 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QBS37_RS18720 3840482..3841060 - 579 WP_021140685.1 hypothetical protein -
QBS37_RS18725 3841517..3841846 - 330 WP_279475520.1 hypothetical protein -
QBS37_RS18730 3842026..3843114 + 1089 WP_279475522.1 Fic family protein -
QBS37_RS18735 3843068..3843409 + 342 WP_258057337.1 hypothetical protein -
QBS37_RS18740 3843488..3843739 + 252 WP_010674977.1 plasmid stabilization protein -
QBS37_RS18745 3844160..3844408 - 249 WP_010674978.1 hypothetical protein -
QBS37_RS18750 3844913..3845167 + 255 WP_005329233.1 helix-turn-helix domain-containing protein Antitoxin
QBS37_RS18755 3845167..3846321 + 1155 WP_279475526.1 type II toxin-antitoxin system HipA family toxin Toxin
QBS37_RS18760 3846332..3846478 + 147 WP_279475528.1 hypothetical protein -
QBS37_RS18770 3847232..3847942 + 711 WP_257724835.1 two-component system response regulator RstA -
QBS37_RS18775 3847964..3849289 + 1326 WP_279475530.1 two-component system sensor histidine kinase RstB -
QBS37_RS18780 3849344..3849526 + 183 WP_005337116.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(4-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(13-65)


Sequences

Toxin        


Download         Length: 385 a.a.        Molecular weight: 43140.36 Da        Isoelectric Point: 7.3970

>T276586 WP_279475526.1 NZ_CP121845:3845167-3846321 [Aeromonas veronii]
MASLTVYMNGYRVGTFTKATNGAHQFQYDESWVKLPGSRPISLSMPLRQQRYQGDEAYNFFDNLLPDNPEVRNRVVARYQ
ADSTQPFDLLSCIGQDSVGALQLVAQGRPVPDVKRIECKPLSDAELEQIMTSYQQGIPLGMVREEDDFRISIAGAQEKTA
LLYLDNRWCLPHAATPTTHIIKLPIGKIESHSYSIDLSQSVENEYLCTLIAKALGLPVPHCFIMQVGKVKALAVERFDRR
YATDRSWIMRLPQEDFCQVLNVPSARKYESHGGPGIADIMTTLLGSATPEQDRYLFMKSQVLFWLLAATDGHAKNFSVFI
EPEGRFRLTPFYDILSMYPAFGGKGLHPRDAKLAMGLTATKGKKIRDRADISSPFLSNGQGDWF

Download         Length: 1155 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9271.66 Da        Isoelectric Point: 9.1571

>AT276586 WP_005329233.1 NZ_CP121845:3844913-3845167 [Aeromonas veronii]
MKVTSAKQLSACLKDARLSQKLSQGKVAGKVGIRQDTVSSFELNPESTKLETLFKILAALELSLDIRPRTDPAENATPGW
KEEW

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References