Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PanAT/DUF4065(antitoxin) |
| Location | 4271238..4272220 | Replicon | chromosome |
| Accession | NZ_CP121798 | ||
| Organism | Aeromonas hydrophila strain YURI 17 | ||
Toxin (Protein)
| Gene name | panT | Uniprot ID | - |
| Locus tag | QBS06_RS20570 | Protein ID | WP_270826561.1 |
| Coordinates | 4271795..4272220 (+) | Length | 142 a.a. |
Antitoxin (Protein)
| Gene name | panA | Uniprot ID | - |
| Locus tag | QBS06_RS20565 | Protein ID | WP_270826560.1 |
| Coordinates | 4271238..4271795 (+) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QBS06_RS20540 | 4266312..4266644 | + | 333 | WP_270826552.1 | hypothetical protein | - |
| QBS06_RS20545 | 4266626..4269031 | + | 2406 | WP_279451103.1 | replication endonuclease | - |
| QBS06_RS20550 | 4269021..4269341 | + | 321 | WP_270826555.1 | hypothetical protein | - |
| QBS06_RS20555 | 4269549..4270613 | + | 1065 | WP_279451104.1 | hypothetical protein | - |
| QBS06_RS20560 | 4270994..4271140 | + | 147 | WP_270826558.1 | hypothetical protein | - |
| QBS06_RS20565 | 4271238..4271795 | + | 558 | WP_270826560.1 | Panacea domain-containing protein | Antitoxin |
| QBS06_RS20570 | 4271795..4272220 | + | 426 | WP_270826561.1 | hypothetical protein | Toxin |
| QBS06_RS20575 | 4272670..4273113 | + | 444 | WP_279451105.1 | BRO family protein | - |
| QBS06_RS20580 | 4273154..4273300 | + | 147 | WP_279452773.1 | hypothetical protein | - |
| QBS06_RS20585 | 4273426..4273926 | + | 501 | WP_279451106.1 | hypothetical protein | - |
| QBS06_RS20590 | 4273934..4274242 | + | 309 | WP_279451107.1 | hypothetical protein | - |
| QBS06_RS20595 | 4274627..4274881 | + | 255 | WP_279451108.1 | hypothetical protein | - |
| QBS06_RS20600 | 4275366..4276409 | - | 1044 | WP_279451109.1 | phage portal protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 4253685..4299867 | 46182 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 142 a.a. Molecular weight: 15564.89 Da Isoelectric Point: 7.0815
>T276577 WP_270826561.1 NZ_CP121798:4271795-4272220 [Aeromonas hydrophila]
MSIALVRRGTLLIPSGATNHLFFVCNDPILYPRNTKASFLAVNISSIAPNIEHDRTCVLDVGDHPFVHHPSFVFYRKAEI
FGAATVGEQIAAGDIQTHAICEEPTFARILAGFDVSPHVTPLIRNFYRKYCLTQPEPSCAP
MSIALVRRGTLLIPSGATNHLFFVCNDPILYPRNTKASFLAVNISSIAPNIEHDRTCVLDVGDHPFVHHPSFVFYRKAEI
FGAATVGEQIAAGDIQTHAICEEPTFARILAGFDVSPHVTPLIRNFYRKYCLTQPEPSCAP
Download Length: 426 bp
Antitoxin
Download Length: 186 a.a. Molecular weight: 21257.05 Da Isoelectric Point: 5.5874
>AT276577 WP_270826560.1 NZ_CP121798:4271238-4271795 [Aeromonas hydrophila]
MFNEERVAQMAAFLLSKRGGRMAYLKLMKLLYLSDRESMSRFGESISGDLMVSMPHGPVLSQTLNLIRGGGEHADGWNEW
ISGEANYEVAIRRNVTGRDDFDLLSDVDLEILTKVWHEFGHMTRYQIRDYTHDHCPEWQDPRGSAYPIKEEDLFLAVGKS
PEVAGAMAQHLREQRQLDEITSRLR
MFNEERVAQMAAFLLSKRGGRMAYLKLMKLLYLSDRESMSRFGESISGDLMVSMPHGPVLSQTLNLIRGGGEHADGWNEW
ISGEANYEVAIRRNVTGRDDFDLLSDVDLEILTKVWHEFGHMTRYQIRDYTHDHCPEWQDPRGSAYPIKEEDLFLAVGKS
PEVAGAMAQHLREQRQLDEITSRLR
Download Length: 558 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|