Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 1955652..1956892 Replicon chromosome
Accession NZ_CP121794
Organism Aeromonas caviae strain FIONA 16800

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag QBS29_RS12430 Protein ID WP_279474488.1
Coordinates 1955652..1956638 (-) Length 329 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag QBS29_RS12435 Protein ID WP_113068875.1
Coordinates 1956638..1956892 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QBS29_RS12415 1951874..1952986 + 1113 WP_279474486.1 hypothetical protein -
QBS29_RS12420 1953094..1953345 + 252 WP_279474487.1 hypothetical protein -
QBS29_RS12425 1954187..1955608 + 1422 WP_043155065.1 IS66-like element ISKpn15 family transposase -
QBS29_RS12430 1955652..1956638 - 987 WP_279474488.1 HipA domain-containing protein Toxin
QBS29_RS12435 1956638..1956892 - 255 WP_113068875.1 helix-turn-helix domain-containing protein Antitoxin
QBS29_RS12440 1957300..1958862 - 1563 WP_279474489.1 ATP-dependent helicase -
QBS29_RS12445 1958865..1960586 - 1722 WP_270813512.1 AAA family ATPase -
QBS29_RS12450 1960757..1961616 + 860 WP_225159511.1 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1942802..1962163 19361
- flank IS/Tn - - 1954202..1955608 1406


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(6-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(13-65)


Sequences

Toxin        


Download         Length: 329 a.a.        Molecular weight: 36876.09 Da        Isoelectric Point: 5.9056

>T276573 WP_279474488.1 NZ_CP121794:c1956638-1955652 [Aeromonas caviae]
MANLWVYMNGYRVGTFTMTTSGAHQFQYDESWVTLPGSRPISLSMPLRQQCYRGDEPYNFFGNLLPDNLEVKNRVVARYQ
ANSTQSFDLLSCIGQDCVGALQLVAQGAPTPDVKRIECKPLSDAELEHILTSYQQGIPLGMVREVEDFRISIAGAQEKTA
LLYRDNRWYLPSAATPTTHIIKLPIGKIESHSYSIDLSQSVENEYLCTLIAKEFGLPVPHCFIMQVGKIKALAVERFDRR
YAADRSWIMRLPQEDFCQVLNVPSVRKYESHGGPSIADIMTTLLGSATPEQDRYLFMKSQVLFWLLAATDGHAKNFSVFI
EPGGEASD

Download         Length: 987 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9437.77 Da        Isoelectric Point: 8.4810

>AT276573 WP_113068875.1 NZ_CP121794:c1956892-1956638 [Aeromonas caviae]
MKVTSAKQLSAYLKDARLLQKYSQGKVADKVGIRQDTVSNFELNPESTKLDTLFKILAALELSLDIKPRTDPPDSPSSGW
KEEW

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References