Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2035447..2036053 Replicon chromosome
Accession NZ_CP121768
Organism Glaesserella parasuis strain d76

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QBK97_RS10015 Protein ID WP_021114171.1
Coordinates 2035447..2035764 (+) Length 106 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QBK97_RS10020 Protein ID WP_021114170.1
Coordinates 2035766..2036053 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QBK97_RS09985 (QBK97_09985) 2032259..2033116 - 858 WP_075630627.1 DUF1837 domain-containing protein -
QBK97_RS09990 (QBK97_09990) 2033167..2033325 - 159 WP_021114175.1 hypothetical protein -
QBK97_RS09995 (QBK97_09995) 2033497..2033889 - 393 WP_234885489.1 efflux RND transporter permease subunit -
QBK97_RS10000 (QBK97_10000) 2033877..2034305 - 429 WP_261576990.1 efflux RND transporter permease subunit -
QBK97_RS10005 (QBK97_10005) 2034350..2034892 - 543 WP_160413775.1 efflux RND transporter permease subunit -
QBK97_RS10010 (QBK97_10010) 2034832..2035230 - 399 WP_075630625.1 efflux RND transporter permease subunit -
QBK97_RS10015 (QBK97_10015) 2035447..2035764 + 318 WP_021114171.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QBK97_RS10020 (QBK97_10020) 2035766..2036053 + 288 WP_021114170.1 putative addiction module antidote protein Antitoxin
QBK97_RS10025 (QBK97_10025) 2036383..2036775 - 393 WP_021114169.1 acrA protein -
QBK97_RS10030 (QBK97_10030) 2036830..2036979 - 150 WP_231401366.1 hypothetical protein -
QBK97_RS10035 (QBK97_10035) 2037006..2037278 - 273 WP_231401367.1 hypothetical protein -
QBK97_RS10040 (QBK97_10040) 2037473..2038624 - 1152 WP_234888060.1 restriction endonuclease subunit S -
QBK97_RS10045 (QBK97_10045) 2038564..2039130 - 567 WP_234885490.1 N-6 DNA methylase -
QBK97_RS10050 (QBK97_10050) 2039229..2040608 - 1380 WP_234885491.1 N-6 DNA methylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(3-89)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11965.65 Da        Isoelectric Point: 9.3816

>T276563 WP_021114171.1 NZ_CP121768:2035447-2035764 [Glaesserella parasuis]
MNVIETTLIFDEWLDNLKDLRAKIQIVTRIRRAENGNFGDHKPLPNTGGVSEIRLDIGKGYRIYYGQIGEITYILTNGGD
KSSQQADIEKAKALFVQIKQQKKEQ

Download         Length: 318 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10484.04 Da        Isoelectric Point: 5.0489

>AT276563 WP_021114170.1 NZ_CP121768:2035766-2036053 [Glaesserella parasuis]
MIETNRFDIVKYLDSDEAIAIYLTQIAETGDSNDFIVALGDVARAKGIAEIAQKTGLARESIYKALTSGSKPRFDTIMRI
MNALNLKPQYAINLS

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References