Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1297575..1298352 Replicon chromosome
Accession NZ_CP121768
Organism Glaesserella parasuis strain d76

Toxin (Protein)


Gene name TacT3 Uniprot ID A0A836YXW5
Locus tag QBK97_RS06275 Protein ID WP_016527794.1
Coordinates 1297852..1298352 (+) Length 167 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag QBK97_RS06270 Protein ID WP_026916906.1
Coordinates 1297575..1297862 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QBK97_RS06250 (QBK97_06250) 1293942..1294442 - 501 WP_021109667.1 CvpA family protein -
QBK97_RS06255 (QBK97_06255) 1294547..1296124 - 1578 WP_279368212.1 FAD-binding protein -
QBK97_RS06260 (QBK97_06260) 1296299..1297036 - 738 WP_021112465.1 peptidoglycan editing factor PgeF -
QBK97_RS06265 (QBK97_06265) 1297040..1297429 - 390 WP_279368213.1 RidA family protein -
QBK97_RS06270 (QBK97_06270) 1297575..1297862 + 288 WP_026916906.1 DUF1778 domain-containing protein Antitoxin
QBK97_RS06275 (QBK97_06275) 1297852..1298352 + 501 WP_016527794.1 GNAT family N-acetyltransferase Toxin
QBK97_RS06280 (QBK97_06280) 1298380..1299381 + 1002 WP_010786647.1 nucleoid-associated protein YejK -
QBK97_RS06285 (QBK97_06285) 1299442..1299777 + 336 WP_016527793.1 outer membrane protein assembly factor BamE -
QBK97_RS06290 (QBK97_06290) 1299931..1301046 + 1116 WP_016527792.1 anhydro-N-acetylmuramic acid kinase -
QBK97_RS06295 (QBK97_06295) 1301058..1301972 + 915 WP_021113663.1 N-acetylmuramic acid 6-phosphate etherase -
QBK97_RS06300 (QBK97_06300) 1302014..1302328 + 315 WP_005710664.1 YqcC family protein -
QBK97_RS06305 (QBK97_06305) 1302325..1303053 + 729 WP_021112446.1 tRNA pseudouridine(65) synthase TruC -
QBK97_RS06310 (QBK97_06310) 1303071..1303226 + 156 WP_021116533.1 YoaH family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(4-88)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 19081.26 Da        Isoelectric Point: 9.2835

>T276562 WP_016527794.1 NZ_CP121768:1297852-1298352 [Glaesserella parasuis]
MKSKFIEEPLTKHHQREAFDCGNLEMNRFFKQYARQSHEKGTSKTYISRHLDSQQIIGFYTITLSALDQQHLPELCKKRF
GYYPIPLFTLARLAVDIRYQKQGIGGMLLVKALKRCAIVAEQVGGIGLLIEAKDEDISRWYQSYGAIPLENMPLTLILLF
DTIKGL

Download         Length: 501 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10893.45 Da        Isoelectric Point: 7.0113

>AT276562 WP_026916906.1 NZ_CP121768:1297575-1297862 [Glaesserella parasuis]
MPQIANALNDRMSIRISTEDKQTLIRAVALTHTNITEFVLQRILPSAREIIQQYDNRQFSPQNLSLIMELLDNPPKANTK
LQQAAKLAKESYNEE

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A836YXW5

Antitoxin

Source ID Structure

References