276540

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1034842..1035479 Replicon chromosome
Accession NZ_CP121700
Organism Methylobacterium indicum strain JDJ13

Toxin (Protein)


Gene name VapC1 Uniprot ID -
Locus tag QBE04_RS04835 Protein ID WP_279358388.1
Coordinates 1035066..1035479 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag QBE04_RS04830 Protein ID WP_279358387.1
Coordinates 1034842..1035069 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QBE04_RS04810 1030368..1031738 - 1371 WP_279358385.1 ethanolamine ammonia-lyase subunit EutB -
QBE04_RS04815 1031862..1032728 - 867 WP_279358386.1 transglutaminase family protein -
QBE04_RS04820 1032901..1033119 + 219 WP_048425630.1 hypothetical protein -
QBE04_RS04825 1033676..1034695 - 1020 WP_082171874.1 SMP-30/gluconolactonase/LRE family protein -
QBE04_RS04830 1034842..1035069 + 228 WP_279358387.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QBE04_RS04835 1035066..1035479 + 414 WP_279358388.1 type II toxin-antitoxin system VapC family toxin Toxin
QBE04_RS04840 1035501..1036571 - 1071 WP_279358389.1 malate/lactate/ureidoglycolate dehydrogenase -
QBE04_RS04845 1036826..1037986 + 1161 WP_279358390.1 ABC transporter substrate-binding protein -
QBE04_RS04850 1038095..1038970 + 876 WP_048425624.1 branched-chain amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-126)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 14955.28 Da        Isoelectric Point: 9.7215

>T276540 WP_279358388.1 NZ_CP121700:1035066-1035479 [Methylobacterium indicum]
VKPRYLLDTNVIIALRRRRPRSVVARLTALRIGEAVMSPVTYGELCFGAEKSVDRDNAFAVLARLVAVVPIEIPEPGETG
RRYGEIRATLGRQGQLIGNNDVWIAAHALAANLTLVTGNVGEFSRVPGLVIEDWTAH

Download         Length: 414 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8456.63 Da        Isoelectric Point: 4.3184

>AT276540 WP_279358387.1 NZ_CP121700:1034842-1035069 [Methylobacterium indicum]
MTVAKLFMSGGSQAVRLPREFRFDGSEVEIFRRGDEVVLRERPANLSVLLDIIDDMPADMLTDLHDGPPQEREGL

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References