276538

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1359642..1360147 Replicon chromosome
Accession NZ_CP121698
Organism Xanthomonas sacchari strain DJ16

Toxin (Protein)


Gene name relE Uniprot ID A0A0A8E0L7
Locus tag QBE03_RS06000 Protein ID WP_017907918.1
Coordinates 1359642..1359899 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A6N7Q778
Locus tag QBE03_RS06005 Protein ID WP_017907919.1
Coordinates 1359896..1360147 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QBE03_RS05970 1354914..1356263 + 1350 WP_279362822.1 aminodeoxychorismate synthase component I -
QBE03_RS05975 1356338..1357399 + 1062 WP_279362824.1 endolytic transglycosylase MltG -
QBE03_RS05980 1357396..1358067 + 672 WP_279362826.1 dTMP kinase -
QBE03_RS05985 1358064..1359026 + 963 WP_279362829.1 DNA polymerase III subunit delta' -
QBE03_RS05990 1359023..1359376 + 354 WP_010342469.1 PilZ domain-containing protein -
QBE03_RS06000 1359642..1359899 - 258 WP_017907918.1 Txe/YoeB family addiction module toxin Toxin
QBE03_RS06005 1359896..1360147 - 252 WP_017907919.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QBE03_RS06010 1360310..1361080 + 771 WP_279363944.1 endonuclease -
QBE03_RS06015 1361261..1361986 - 726 WP_279362832.1 helix-turn-helix transcriptional regulator -
QBE03_RS06020 1362000..1362557 + 558 WP_279362835.1 nuclear transport factor 2 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1359642..1370721 11079


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10223.75 Da        Isoelectric Point: 9.6589

>T276538 WP_017907918.1 NZ_CP121698:c1359899-1359642 [Xanthomonas sacchari]
VTLQFSDNAWEDYLYWQQADKKMLKRINDLIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKVEHGVLLIAQV
RYHYV

Download         Length: 258 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9324.59 Da        Isoelectric Point: 5.1186

>AT276538 WP_017907919.1 NZ_CP121698:c1360147-1359896 [Xanthomonas sacchari]
MDTITYSAARAALADTMDRVVNNHEPVIITRSREQAVVMLSLEDYKAMEETAYLLRSPKNAQRLLESIAQLESGRGKARE
LSE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0A8E0L7

Antitoxin

Source ID Structure
AlphaFold DB A0A6N7Q778

References