Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-PrlF
Location 8335311..8335851 Replicon chromosome
Accession NZ_CP121695
Organism Bradyrhizobium sp. CB1650

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QA641_RS39410 Protein ID WP_279372705.1
Coordinates 8335513..8335851 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QA641_RS39405 Protein ID WP_279372704.1
Coordinates 8335311..8335526 (+) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA641_RS39390 (QA641_39390) 8330575..8332233 + 1659 WP_279372701.1 recombinase family protein -
QA641_RS39395 (QA641_39395) 8332404..8334101 + 1698 WP_279372702.1 hypothetical protein -
QA641_RS39400 (QA641_39400) 8334851..8335210 + 360 WP_279372703.1 helix-turn-helix transcriptional regulator -
QA641_RS39405 (QA641_39405) 8335311..8335526 + 216 WP_279372704.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
QA641_RS39410 (QA641_39410) 8335513..8335851 + 339 WP_279372705.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QA641_RS39415 (QA641_39415) 8336485..8337075 + 591 WP_279372706.1 hypothetical protein -
QA641_RS39420 (QA641_39420) 8337251..8337760 + 510 WP_279372707.1 hypothetical protein -
QA641_RS39425 (QA641_39425) 8337831..8337968 + 138 WP_279372708.1 hypothetical protein -
QA641_RS39430 (QA641_39430) 8337972..8338793 + 822 WP_279372709.1 metallophosphoesterase -
QA641_RS39435 (QA641_39435) 8338883..8339191 + 309 WP_279372710.1 hypothetical protein -
QA641_RS39440 (QA641_39440) 8339626..8340366 + 741 WP_279372711.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(5-109)

Antitoxin

PrlF antitoxin

(4-52)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12376.26 Da        Isoelectric Point: 10.4044

>T276536 WP_279372705.1 NZ_CP121695:8335513-8335851 [Bradyrhizobium sp. CB1650]
MPPFRQGDVVRVPFPYTDRSTRQHRPALVVSTGGIGENENLIWVVMITSAENRTWPGDLAIGRYEEAGLPAPSIIRSCKI
ATIEARHAERLGRIKPRLTTEVVSAIRSILGS

Download         Length: 339 bp

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 7834.89 Da        Isoelectric Point: 4.6684

>AT276536 WP_279372704.1 NZ_CP121695:8335311-8335526 [Bradyrhizobium sp. CB1650]
MITSKLTTKAQTTIPQAVRSALHLKEGDEIAYTITGDKVVMTKAELTLVDDPFATFSEWDSEADRKAYATL

Download         Length: 216 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References