Detailed information of TA system TA276535

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 8036608..8038126
• Replicon: chromosome
• Accession: NZ_CP121695
• Organism: Bradyrhizobium sp. CB1650

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: QA641_RS38045
• Protein ID: WP_279372498.1
• Coordinates: 8036608..8037489 (-)
• Length: 294 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: QA641_RS38050
• Protein ID: WP_279372499.1
• Coordinates: 8037482..8038126 (-)
• Length: 215 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QA641_RS38030 (QA641_38030)	8032013..8034484	-	2472	WP_279377920.1	EAL domain-containing protein	-
QA641_RS38035 (QA641_38035)	8034918..8035929	-	1012	Protein_7555	IS5 family transposase	-
QA641_RS38040 (QA641_38040)	8035929..8036396	+	468	WP_279372497.1	hypothetical protein	-
QA641_RS38045 (QA641_38045)	8036608..8037489	-	882	WP_279372498.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
QA641_RS38050 (QA641_38050)	8037482..8038126	-	645	WP_279372499.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
QA641_RS38055 (QA641_38055)	8038308..8038508	-	201	WP_279372500.1	hypothetical protein	-
QA641_RS38060 (QA641_38060)	8039195..8039746	+	552	WP_279372501.1	hypothetical protein	-
QA641_RS38065 (QA641_38065)	8039751..8041505	-	1755	WP_279372502.1	phosphoenolpyruvate hydrolase family protein	-
QA641_RS38070 (QA641_38070)	8041564..8042676	-	1113	WP_279372503.1	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	8034906..8035748	842

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (38-262)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (13-56)

Sequences

Toxin

Protein

• Length: 294 a.a.
• Molecular weight: 32451.16 Da
• Isoelectric Point: 5.5615

>T276535 WP_279372498.1 NZ_CP121695:c8037489-8036608 [Bradyrhizobium sp. CB1650]
MANPTKNVAASVRARLLTLSKERNQPFDLLLTRYVLERLLYRLGSTDYRNRFVLKGAMLLATWVDNQFRPTRDLDLLGSG
DPDPEALLAIFKEIAAVDAADGVIFDPASFTVDRIRDENEYGGVRIKGNATVDNARVRVVIDIAFGDAIEPGVQETDLPV
LLDFPAPKLRSYPRETVIAEKFQAMVALGLANSRMKDFYDVWVLIRSYKFEGDTLARAIKATFARRKTEIPTVLPDAFTP
AFTEDNGKTDQWTAFTKQVAIDPGSLTDVANTLAEFLMPQAAKSRAMKGGATA

Nucleotide

• Length: 882 bp

Antitoxin

Protein

• Length: 215 a.a.
• Molecular weight: 23466.17 Da
• Isoelectric Point: 10.7810

>AT276535 WP_279372499.1 NZ_CP121695:c8038126-8037482 [Bradyrhizobium sp. CB1650]
MAKPSSTQQDRATEFLKERGIARLSELATAGVTAATIARMKQKGLIVQLGRGLYQLSDAPIDTHHSLAEAAKRVPKGVVA
LTSALAFHDLTDTIPSMVWLAIGPKDRQPLSTNPPMQFVRFSPARLQEGVEIHTIEGCPVKIFSPAKTVVDLFRYRRSAG
TRYRHSTGLNLALEGLREALRTRKAKPSEIADFARKAGVWKAMQPYMDAMTANG

Nucleotide

• Length: 645 bp