Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 3708586..3709102 Replicon chromosome
Accession NZ_CP121679
Organism Ancylobacter sp. WKF20

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag AncyloWKF20_RS17125 Protein ID WP_279315182.1
Coordinates 3708821..3709102 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AncyloWKF20_RS17120 Protein ID WP_279315181.1
Coordinates 3708586..3708831 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AncyloWKF20_RS17100 (AncyloWKF20_17100) 3703882..3704412 - 531 WP_279315177.1 chromate transporter -
AncyloWKF20_RS17105 (AncyloWKF20_17105) 3704409..3705014 - 606 WP_279315178.1 chromate transporter -
AncyloWKF20_RS17110 (AncyloWKF20_17110) 3705172..3705675 + 504 WP_279315179.1 MmcB family DNA repair protein -
AncyloWKF20_RS17115 (AncyloWKF20_17115) 3705765..3708509 + 2745 WP_279315180.1 DNA mismatch repair protein MutS -
AncyloWKF20_RS17120 (AncyloWKF20_17120) 3708586..3708831 + 246 WP_279315181.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
AncyloWKF20_RS17125 (AncyloWKF20_17125) 3708821..3709102 + 282 WP_279315182.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AncyloWKF20_RS17130 (AncyloWKF20_17130) 3709105..3709659 - 555 WP_279315183.1 cysteine hydrolase family protein -
AncyloWKF20_RS17135 (AncyloWKF20_17135) 3709833..3710246 - 414 WP_279318012.1 carboxymuconolactone decarboxylase family protein -
AncyloWKF20_RS17140 (AncyloWKF20_17140) 3710182..3710610 - 429 WP_279315184.1 MerR family transcriptional regulator -
AncyloWKF20_RS17145 (AncyloWKF20_17145) 3710743..3713421 - 2679 WP_279315185.1 pyruvate, phosphate dikinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-71)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10816.63 Da        Isoelectric Point: 10.7380

>T276528 WP_279315182.1 NZ_CP121679:3708821-3709102 [Ancylobacter sp. WKF20]
MSYELEFLPSARKEWDKLGATLRQQFKKKLAERLIRPRVPADALSGMPDHYKIKLRAAGYRLVYRVEEARITVVVVAVGK
RERGDVYEAARQR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8765.11 Da        Isoelectric Point: 4.7672

>AT276528 WP_279315181.1 NZ_CP121679:3708586-3708831 [Ancylobacter sp. WKF20]
MQRVEAEMAVSVSDLKKNPTAIVEDARGAAVAVLNHNRVMAYMVPAATYEAMIDALDDRALVEIAKARAGERGVPVRLDE
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References