Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 350059..350705 Replicon chromosome
Accession NZ_CP121679
Organism Ancylobacter sp. WKF20

Toxin (Protein)


Gene name VapC1 Uniprot ID -
Locus tag AncyloWKF20_RS01615 Protein ID WP_279316233.1
Coordinates 350295..350705 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag AncyloWKF20_RS01610 Protein ID WP_279316232.1
Coordinates 350059..350295 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AncyloWKF20_RS01585 (AncyloWKF20_01585) 345527..345985 + 459 WP_279316228.1 DoxX family protein -
AncyloWKF20_RS01590 (AncyloWKF20_01590) 346158..346907 - 750 WP_279316229.1 ABC transporter permease -
AncyloWKF20_RS01595 (AncyloWKF20_01595) 346907..347629 - 723 WP_279316230.1 ABC transporter permease -
AncyloWKF20_RS01600 (AncyloWKF20_01600) 347703..348428 - 726 WP_279317849.1 ABC transporter substrate-binding protein -
AncyloWKF20_RS01605 (AncyloWKF20_01605) 348770..349984 + 1215 WP_279316231.1 Mrp/NBP35 family ATP-binding protein -
AncyloWKF20_RS01610 (AncyloWKF20_01610) 350059..350295 + 237 WP_279316232.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
AncyloWKF20_RS01615 (AncyloWKF20_01615) 350295..350705 + 411 WP_279316233.1 type II toxin-antitoxin system VapC family toxin Toxin
AncyloWKF20_RS01620 (AncyloWKF20_01620) 350861..351952 + 1092 WP_279316234.1 TRAP transporter substrate-binding protein -
AncyloWKF20_RS01625 (AncyloWKF20_01625) 352076..353200 + 1125 WP_279316235.1 TRAP transporter substrate-binding protein DctP -
AncyloWKF20_RS01630 (AncyloWKF20_01630) 353249..354349 + 1101 WP_279316236.1 TRAP transporter substrate-binding protein -
AncyloWKF20_RS01635 (AncyloWKF20_01635) 354421..355344 - 924 WP_279316237.1 DMT family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-48)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14929.26 Da        Isoelectric Point: 6.9833

>T276526 WP_279316233.1 NZ_CP121679:350295-350705 [Ancylobacter sp. WKF20]
MAARYLLDTNIIIALRRRRPSSLVERLSRLQPGEVVMSAVVYGELCYGAEKSVRRDEAQEVLQRLTQAIPVDPLPGDAPL
VYGRVRAALEARGAIIGGNDLWIAAHALARGLVLVTGNVREFGRVPDLVVEDWSVD

Download         Length: 411 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8589.77 Da        Isoelectric Point: 4.3766

>AT276526 WP_279316232.1 NZ_CP121679:350059-350295 [Ancylobacter sp. WKF20]
MSTAKVFISGNSQAVRLPKEFRLKGPEVEIFRRGDEIVLREKPEGLAHLLDILDALPEDVLTEAPDDPPPAPVDSGER

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References