Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 7703398..7704101 Replicon chromosome
Accession NZ_CP121668
Organism Bradyrhizobium sp. CB2312

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA642_RS37390 Protein ID WP_283081374.1
Coordinates 7703679..7704101 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA642_RS37385 Protein ID WP_283081373.1
Coordinates 7703398..7703682 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA642_RS37365 (QA642_37365) 7698470..7699444 - 975 WP_283081369.1 sugar ABC transporter permease -
QA642_RS37370 (QA642_37370) 7699444..7700529 - 1086 WP_283081370.1 ABC transporter ATP-binding protein -
QA642_RS37375 (QA642_37375) 7700542..7701618 - 1077 WP_283081371.1 ABC transporter ATP-binding protein -
QA642_RS37380 (QA642_37380) 7701615..7703165 - 1551 WP_283081372.1 glycerol-3-phosphate dehydrogenase -
QA642_RS37385 (QA642_37385) 7703398..7703682 + 285 WP_283081373.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QA642_RS37390 (QA642_37390) 7703679..7704101 + 423 WP_283081374.1 type II toxin-antitoxin system VapC family toxin Toxin
QA642_RS37395 (QA642_37395) 7704106..7704951 - 846 WP_235539959.1 DeoR/GlpR family DNA-binding transcription regulator -
QA642_RS37400 (QA642_37400) 7705040..7705726 - 687 WP_283081375.1 HAD-IA family hydrolase -
QA642_RS37405 (QA642_37405) 7705881..7706333 + 453 WP_283081376.1 nuclear transport factor 2 family protein -
QA642_RS37410 (QA642_37410) 7706559..7706750 - 192 WP_195799755.1 hypothetical protein -
QA642_RS37415 (QA642_37415) 7706941..7707351 - 411 WP_283081377.1 acyl-CoA thioesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(15-77)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15325.73 Da        Isoelectric Point: 7.2069

>T276523 WP_283081374.1 NZ_CP121668:7703679-7704101 [Bradyrhizobium sp. CB2312]
VNLLLDTNVLSEVRRPAPSLKVLAWLDTIDEDRAFISVASIAELRRGIALLKDGRRRTALAAWLAHDLPARFAERVLPID
HAVADRWGDLMAESRRTGVALSVMDGFFAATALANSLTLVTRNVKDFAALGVPLLNPWDA

Download         Length: 423 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10320.61 Da        Isoelectric Point: 6.7251

>AT276523 WP_283081373.1 NZ_CP121668:7703398-7703682 [Bradyrhizobium sp. CB2312]
MADHNTAPDTPPINDTWTLANAKARLSELVDRAQTGPQVITRHGKPNAVVVSAQEWARKTARKGTLAEFLLASPLRGADL
ELDRVHDTPRDEMP

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References