Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 536731..537359 Replicon chromosome
Accession NZ_CP121668
Organism Bradyrhizobium sp. CB2312

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA642_RS02570 Protein ID WP_283083246.1
Coordinates 536958..537359 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA642_RS02565 Protein ID WP_283083245.1
Coordinates 536731..536961 (+) Length 77 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA642_RS02550 (QA642_02550) 533338..534033 - 696 WP_283083243.1 hypothetical protein -
QA642_RS02555 (QA642_02555) 534204..535232 + 1029 WP_283083244.1 LysM peptidoglycan-binding domain-containing protein -
QA642_RS02560 (QA642_02560) 535384..536655 + 1272 WP_283087137.1 Spy/CpxP family protein refolding chaperone -
QA642_RS02565 (QA642_02565) 536731..536961 + 231 WP_283083245.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QA642_RS02570 (QA642_02570) 536958..537359 + 402 WP_283083246.1 PIN domain-containing protein Toxin
QA642_RS02575 (QA642_02575) 537441..538268 - 828 WP_283083247.1 hypothetical protein -
QA642_RS02580 (QA642_02580) 538534..540981 - 2448 WP_283083248.1 adenylate/guanylate cyclase domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-116)

Antitoxin

(5-36)


Sequences


Toxin        


Download         Length: 134 a.a.        Molecular weight: 14607.53 Da        Isoelectric Point: 6.2130

>T276521 WP_283083246.1 NZ_CP121668:536958-537359 [Bradyrhizobium sp. CB2312]
VSAFFDSNILIYAYSTDTRRQRALTTIAGGGIISAQVLNEFTNVLRKKQRQDWPVIEAAVQSLRFRFPDIVPLTSDTHTA
ALALARDHTLAFYDALIVAAAIEAGCDTLYSEDLQHSRSFSGLTIVNPFLGST

Download         Length: 402 bp


Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8683.91 Da        Isoelectric Point: 5.1617

>AT276521 WP_283083245.1 NZ_CP121668:536731-536961 [Bradyrhizobium sp. CB2312]
VLVSKWGNSLAVRLPKALVEALKLSPGDELNVVEASKGRLAVEKVDKRAEFLRQVEQFQFPLPEDYKFDRDEANER

Download         Length: 231 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References