Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 7061806..7062518 Replicon chromosome
Accession NZ_CP121667
Organism Bradyrhizobium pachyrhizi strain CB1923

Toxin (Protein)


Gene name vapC Uniprot ID A0A844T9Y2
Locus tag QA639_RS33525 Protein ID WP_028337910.1
Coordinates 7062081..7062518 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA639_RS33520 Protein ID WP_283088169.1
Coordinates 7061806..7062084 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA639_RS33495 (QA639_33495) 7058168..7059190 - 1023 WP_283090655.1 IS3 family transposase -
QA639_RS33500 (QA639_33500) 7059118..7059270 - 153 Protein_6647 transposase -
QA639_RS33505 (QA639_33505) 7059497..7060098 - 602 Protein_6648 IS21-like element helper ATPase IstB -
QA639_RS33510 (QA639_33510) 7060230..7061245 - 1016 Protein_6649 IS110 family transposase -
QA639_RS33515 (QA639_33515) 7061398..7061688 + 291 WP_157348971.1 hypothetical protein -
QA639_RS33520 (QA639_33520) 7061806..7062084 + 279 WP_283088169.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QA639_RS33525 (QA639_33525) 7062081..7062518 + 438 WP_028337910.1 type II toxin-antitoxin system VapC family toxin Toxin
QA639_RS33530 (QA639_33530) 7062515..7063411 + 897 WP_283088170.1 hypothetical protein -
QA639_RS33535 (QA639_33535) 7063554..7063847 - 294 Protein_6654 transposase -
QA639_RS33540 (QA639_33540) 7063910..7064083 + 174 WP_244486498.1 hypothetical protein -
QA639_RS33545 (QA639_33545) 7064415..7064631 + 217 Protein_6656 hypothetical protein -
QA639_RS33550 (QA639_33550) 7064840..7066432 - 1593 WP_283090656.1 ATP-binding protein -
QA639_RS33555 (QA639_33555) 7066917..7067159 - 243 WP_283088171.1 multicopper oxidase domain-containing protein -
QA639_RS33560 (QA639_33560) 7067180..7067278 - 99 WP_283088172.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 7055353..7063718 8365


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(13-71)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15817.13 Da        Isoelectric Point: 4.4902

>T276520 WP_028337910.1 NZ_CP121667:7062081-7062518 [Bradyrhizobium pachyrhizi]
MNVLLDTNVLSEVRRPAPDPKVLAWLDTIDEDRAFISVASIAELRRGIALMDDGRRREALSAWLAEDLPARFAGRILSID
PAIAGRWGDLMAQARQSGFALSVMDGFFAATALDRELVLATRNTKDFAPLGVPLLNPWTDEGALG

Download         Length: 438 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10327.67 Da        Isoelectric Point: 5.8752

>AT276520 WP_283088169.1 NZ_CP121667:7061806-7062084 [Bradyrhizobium pachyrhizi]
VTASRKTPAPETDHWTVAGAKARLSEVIERAQTDPQIITRYGKPSVVIVSAEEWARKTDRKGTLAEFLMASPLRDADLDL
ERVRDQPRDLDL

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A844T9Y2

Antitoxin

Source ID Structure

References