Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 748244..748890 Replicon chromosome
Accession NZ_CP121666
Organism Bradyrhizobium sp. CB1717

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA649_RS03435 Protein ID WP_283022970.1
Coordinates 748244..748657 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA649_RS03440 Protein ID WP_283022971.1
Coordinates 748654..748890 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA649_RS03415 (QA649_03415) 744459..745550 + 1092 WP_283022967.1 branched-chain amino acid ABC transporter permease -
QA649_RS03420 (QA649_03420) 745540..746271 + 732 WP_283022968.1 ABC transporter ATP-binding protein -
QA649_RS03425 (QA649_03425) 746264..746962 + 699 WP_283022969.1 ABC transporter ATP-binding protein -
QA649_RS03430 (QA649_03430) 747184..748116 + 933 WP_283026035.1 transposase -
QA649_RS03435 (QA649_03435) 748244..748657 - 414 WP_283022970.1 PIN domain-containing protein Toxin
QA649_RS03440 (QA649_03440) 748654..748890 - 237 WP_283022971.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QA649_RS03445 (QA649_03445) 749017..749865 - 849 WP_283022972.1 DUF3883 domain-containing protein -
QA649_RS03450 (QA649_03450) 749972..751474 - 1503 WP_283022973.1 murein L,D-transpeptidase family protein -
QA649_RS03455 (QA649_03455) 751975..752937 - 963 WP_283022974.1 acetyl-CoA carboxylase carboxyltransferase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-113)

Antitoxin

SpoVT-AbrB domain

(5-34)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 14623.53 Da        Isoelectric Point: 4.1747

>T276519 WP_283022970.1 NZ_CP121666:c748657-748244 [Bradyrhizobium sp. CB1717]
VTAFLDTNILVYAQQRGTKAKISQDLIDEGGTISVQVLNELANVLSKKQGRSWRDIELVFDDIDNALDPVLPLTATTSRA
ALALARDDGFAFYDALIVAAAIEAGCDILYSEDMQHGRSIGGLTIVNPFLGSASPSP

Download         Length: 414 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9033.26 Da        Isoelectric Point: 6.4000

>AT276519 WP_283022971.1 NZ_CP121666:c748890-748654 [Bradyrhizobium sp. CB1717]
MQVSKWGNSLAVRLPKALVEELGLKEGDELEVVAARKGAIEVETKEERRRRAIENMRARNWPPLPADYKFDRDEANER

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References