Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1316314..1316897 Replicon plasmid pCB3090_1
Accession NZ_CP121663
Organism Rhizobium sp. CB3090

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA646_RS24810 Protein ID WP_283059391.1
Coordinates 1316511..1316897 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A0T6ZM79
Locus tag QA646_RS24805 Protein ID WP_017958375.1
Coordinates 1316314..1316514 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA646_RS24795 (QA646_24795) 1312318..1313850 - 1533 WP_283059389.1 FAD-dependent monooxygenase -
QA646_RS24800 (QA646_24800) 1315372..1316010 + 639 WP_283059390.1 GGDEF domain-containing protein -
QA646_RS24805 (QA646_24805) 1316314..1316514 + 201 WP_017958375.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QA646_RS24810 (QA646_24810) 1316511..1316897 + 387 WP_283059391.1 type II toxin-antitoxin system VapC family toxin Toxin
QA646_RS24815 (QA646_24815) 1317014..1317258 - 245 Protein_1195 myo-inosose-2 dehydratase -
QA646_RS24820 (QA646_24820) 1317861..1318772 + 912 WP_283059392.1 hypothetical protein -
QA646_RS24825 (QA646_24825) 1319721..1320617 - 897 WP_283059393.1 GntR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA 1..1773801 1773801


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14179.37 Da        Isoelectric Point: 7.4769

>T276518 WP_283059391.1 NZ_CP121663:1316511-1316897 [Rhizobium sp. CB3090]
VILADTSIWIDHFRQADAELRTIIENDRLLCHPAVVGELALGSLRDRGRVITFLAAQRQAFVATHDEVMIMIDRHGIFSM
GIGYTDAHLLASILLDPRAALWTRDKRLQAAAEKAGASLHTPVKARNT

Download         Length: 387 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7124.23 Da        Isoelectric Point: 11.3760

>AT276518 WP_017958375.1 NZ_CP121663:1316314-1316514 [Rhizobium sp. CB3090]
MRSTINLDDTLMERARSLTGTKETAALVRQALETLVRVESGKRLIALGGTMPDAEAAPRRRSAAAK

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0T6ZM79

References