Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 2449071..2449735 Replicon chromosome
Accession NZ_CP121662
Organism Rhizobium sp. CB3090

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA646_RS11895 Protein ID WP_283055660.1
Coordinates 2449325..2449735 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA646_RS11890 Protein ID WP_283055659.1
Coordinates 2449071..2449325 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA646_RS11860 (QA646_11860) 2444621..2445202 + 582 WP_283055654.1 NAD(P)H-dependent oxidoreductase -
QA646_RS11865 (QA646_11865) 2445248..2445637 - 390 WP_283058854.1 RidA family protein -
QA646_RS11870 (QA646_11870) 2445699..2446595 - 897 WP_283055655.1 DMT family transporter -
QA646_RS11875 (QA646_11875) 2446806..2447243 + 438 WP_283055656.1 hypothetical protein -
QA646_RS11880 (QA646_11880) 2447275..2447892 - 618 WP_283055657.1 alpha/beta hydrolase -
QA646_RS11885 (QA646_11885) 2447907..2448839 - 933 WP_283055658.1 VOC family protein -
QA646_RS11890 (QA646_11890) 2449071..2449325 + 255 WP_283055659.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QA646_RS11895 (QA646_11895) 2449325..2449735 + 411 WP_283055660.1 type II toxin-antitoxin system VapC family toxin Toxin
QA646_RS11900 (QA646_11900) 2449729..2450430 - 702 WP_283055661.1 uracil-DNA glycosylase -
QA646_RS11905 (QA646_11905) 2450606..2451289 - 684 WP_283055662.1 septation protein IspZ -
QA646_RS11910 (QA646_11910) 2451300..2453747 - 2448 WP_283055663.1 FAD-dependent oxidoreductase -
QA646_RS11915 (QA646_11915) 2453757..2454635 - 879 WP_283055664.1 choline kinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-62)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15141.27 Da        Isoelectric Point: 6.8816

>T276514 WP_283055660.1 NZ_CP121662:2449325-2449735 [Rhizobium sp. CB3090]
MYLIDTNVISEARRGTPEAISWLRTADPSTVYLSVITLGEVMRGIALKRKSDPRAAAHLEEWLRKLRHDHSGRILPITDQ
IAVEWGRVAALRPRGGADELIAATAIVHDLIVVTRNISNFDDTGVSVINPWDQTSY

Download         Length: 411 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9404.46 Da        Isoelectric Point: 4.5781

>AT276514 WP_283055659.1 NZ_CP121662:2449071-2449325 [Rhizobium sp. CB3090]
MDWPLQDAKNQFSRVVQKARSEGPQTVTLRGERAVVVLSAEDYDALRANRPSLVDDLLSGPAWDDEFADAVTKRDKTPSR
DIAF

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References