Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1577183..1577847 Replicon chromosome
Accession NZ_CP121662
Organism Rhizobium sp. CB3090

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA646_RS07705 Protein ID WP_283058459.1
Coordinates 1577407..1577847 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA646_RS07700 Protein ID WP_283058458.1
Coordinates 1577183..1577410 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA646_RS07675 (QA646_07675) 1572595..1573422 - 828 WP_283058453.1 inositol monophosphatase -
QA646_RS07680 (QA646_07680) 1573508..1574269 - 762 WP_283058454.1 Fic family protein -
QA646_RS07685 (QA646_07685) 1574343..1575218 - 876 WP_283058455.1 tRNA 2-thiocytidine(32) synthetase TtcA -
QA646_RS07690 (QA646_07690) 1575279..1576208 - 930 WP_283058456.1 glutaminase -
QA646_RS07695 (QA646_07695) 1576280..1576897 - 618 WP_283058457.1 30S ribosomal protein S4 -
QA646_RS07700 (QA646_07700) 1577183..1577410 + 228 WP_283058458.1 CopG family transcriptional regulator Antitoxin
QA646_RS07705 (QA646_07705) 1577407..1577847 + 441 WP_283058459.1 VapC toxin family PIN domain ribonuclease Toxin
QA646_RS07710 (QA646_07710) 1577854..1579371 - 1518 WP_283058460.1 ATP-binding protein -
QA646_RS07715 (QA646_07715) 1579500..1580645 - 1146 WP_283058462.1 alpha-hydroxy acid oxidase -
QA646_RS07720 (QA646_07720) 1580734..1581198 - 465 WP_283058463.1 GNAT family N-acetyltransferase -
QA646_RS07725 (QA646_07725) 1581201..1582001 - 801 WP_283058464.1 glutamate racemase -
QA646_RS07730 (QA646_07730) 1581982..1582824 - 843 WP_283058466.1 RNA methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(2-129)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 15809.01 Da        Isoelectric Point: 6.6384

>T276513 WP_283058459.1 NZ_CP121662:1577407-1577847 [Rhizobium sp. CB3090]
VTFLLDVNVLIALFDPAHVSHDIAHNWFSSTGNQSWATCPLTENGVIRILGQSSYPNSPGPPSTVVPLIEELRRLPGHEF
WADDISLTDASLIDPARLLTPGQVTDSYLLALAKFRRGKLATLDRRLSTAAVKDGRAALHIIGSAT

Download         Length: 441 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8194.48 Da        Isoelectric Point: 8.8948

>AT276513 WP_283058458.1 NZ_CP121662:1577183-1577410 [Rhizobium sp. CB3090]
MRTTLAIDDDVLAAAKAMAEQQRRSVGDVISDLARRSLSRPQMGAERNGIPLLVPKSSTPPITLEIVNKLRDELP

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References