Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 420822..421456 Replicon chromosome
Accession NZ_CP121662
Organism Rhizobium sp. CB3090

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA646_RS02045 Protein ID WP_283057298.1
Coordinates 421052..421456 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA646_RS02040 Protein ID WP_283057297.1
Coordinates 420822..421052 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA646_RS02010 (QA646_02010) 415939..416955 - 1017 WP_283057291.1 polyprenyl synthetase family protein -
QA646_RS02015 (QA646_02015) 417064..417294 + 231 WP_283057292.1 DUF2007 domain-containing protein -
QA646_RS02020 (QA646_02020) 417303..418079 + 777 WP_283057293.1 methyltransferase -
QA646_RS02025 (QA646_02025) 418129..419475 - 1347 WP_283057294.1 Nramp family divalent metal transporter -
QA646_RS02030 (QA646_02030) 419690..420550 + 861 WP_283057295.1 S49 family peptidase -
QA646_RS02035 (QA646_02035) 420567..420758 + 192 WP_283057296.1 hypothetical protein -
QA646_RS02040 (QA646_02040) 420822..421052 + 231 WP_283057297.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QA646_RS02045 (QA646_02045) 421052..421456 + 405 WP_283057298.1 PIN domain-containing protein Toxin
QA646_RS02050 (QA646_02050) 421670..422629 + 960 WP_283057299.1 glycine--tRNA ligase subunit alpha -
QA646_RS02055 (QA646_02055) 422738..423289 + 552 WP_283057300.1 LemA family protein -
QA646_RS02060 (QA646_02060) 423377..424633 + 1257 WP_283057301.1 3-phosphoshikimate 1-carboxyvinyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-116)

Antitoxin

SpoVT-AbrB domain

(5-37)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15247.54 Da        Isoelectric Point: 5.6436

>T276512 WP_283057298.1 NZ_CP121662:421052-421456 [Rhizobium sp. CB3090]
MRALPPFLDTNVLLYAFTDDQRAQKAQLLLAEPFTISVQALNEFANVARKKLHLPWKRIHEAIRTIVELSTSVVAIDEKT
TLSALNLAERYNFSFYDAAMVAAALQANCERYYSEDLHDCLIVETRLTIINPFS

Download         Length: 405 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8617.74 Da        Isoelectric Point: 5.1468

>AT276512 WP_283057297.1 NZ_CP121662:420822-421052 [Rhizobium sp. CB3090]
MQVAKWGNSLAIRIPSAVAEALDLKEGDDVVVRIGADSAFEIERDDRRQKALEKVKSFKITLPTDWKFDRDEANSR

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References