276511

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 1591322..1591890 Replicon plasmid pCB3126_1
Accession NZ_CP121660
Organism Sinorhizobium terangae strain CB3126

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag QA637_RS26055 Protein ID WP_153437057.1
Coordinates 1591645..1591890 (-) Length 82 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag QA637_RS26050 Protein ID WP_153437056.1
Coordinates 1591322..1591645 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA637_RS26030 (QA637_26030) 1586837..1588288 - 1452 WP_283065621.1 alpha,alpha-trehalose-phosphate synthase (UDP-forming) -
QA637_RS26035 (QA637_26035) 1588372..1589169 - 798 WP_283065623.1 trehalose-phosphatase -
QA637_RS26040 (QA637_26040) 1589679..1589921 - 243 Protein_1466 hypothetical protein -
QA637_RS26045 (QA637_26045) 1591037..1591321 + 285 WP_283065625.1 hypothetical protein -
QA637_RS26050 (QA637_26050) 1591322..1591645 - 324 WP_153437056.1 BrnA antitoxin family protein Antitoxin
QA637_RS26055 (QA637_26055) 1591645..1591890 - 246 WP_153437057.1 BrnT family toxin Toxin
QA637_RS26060 (QA637_26060) 1591982..1592371 + 390 WP_283065628.1 DUF5681 domain-containing protein -
QA637_RS26065 (QA637_26065) 1592295..1592479 + 185 Protein_1471 DNA packaging protein -
QA637_RS26070 (QA637_26070) 1592516..1592782 + 267 WP_167528143.1 hypothetical protein -
QA637_RS26075 (QA637_26075) 1593390..1593509 - 120 Protein_1473 ATP-dependent DNA ligase -
QA637_RS26080 (QA637_26080) 1593635..1594030 + 396 WP_153437060.1 PRC-barrel domain-containing protein -
QA637_RS26085 (QA637_26085) 1594186..1594449 + 264 WP_153437061.1 hypothetical protein -
QA637_RS26090 (QA637_26090) 1594429..1594800 - 372 WP_283065632.1 low affinity iron permease family protein -
QA637_RS26095 (QA637_26095) 1595244..1595417 + 174 WP_283065633.1 hypothetical protein -
QA637_RS26100 (QA637_26100) 1595643..1595954 + 312 WP_153437063.1 PepSY domain-containing protein -
QA637_RS26105 (QA637_26105) 1595995..1596591 + 597 WP_283065636.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB / katA 1..2093508 2093508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-77)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(27-101)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9021.58 Da        Isoelectric Point: 8.7696

>T276511 WP_153437057.1 NZ_CP121660:c1591890-1591645 [Sinorhizobium terangae]
MKIIWDEPKRIANIEKHGLDFADLSLEFFLASLVVPAKNGRSKAIGRLEDGTVVVIFVTLGTEALSVISMRPARKDERNL
L

Download         Length: 246 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 12289.99 Da        Isoelectric Point: 10.2650

>AT276511 WP_153437056.1 NZ_CP121660:c1591645-1591322 [Sinorhizobium terangae]
MAIKYKRQEEFRPGRGYTKKDWDAVSDNPPLTEEEMKQARPFKEVFPDLSEKIEKAVRGRPKGDTTKTPVTIRLDPDVVE
HYKATGRGWQSRMNDDLRKAAGLKKAG

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References