276510

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1543776..1544437 Replicon plasmid pCB3126_1
Accession NZ_CP121660
Organism Sinorhizobium terangae strain CB3126

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA637_RS25830 Protein ID WP_283065574.1
Coordinates 1544033..1544437 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA637_RS25825 Protein ID WP_283065572.1
Coordinates 1543776..1544036 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA637_RS25785 (QA637_25785) 1539430..1539566 + 137 Protein_1415 DNA helicase -
QA637_RS25790 (QA637_25790) 1539626..1540108 - 483 WP_283067352.1 N-acetyltransferase -
QA637_RS25795 (QA637_25795) 1540226..1541020 - 795 WP_283065566.1 class I SAM-dependent methyltransferase -
QA637_RS25800 (QA637_25800) 1541119..1541283 + 165 WP_283065567.1 hypothetical protein -
QA637_RS25805 (QA637_25805) 1541751..1541882 + 132 Protein_1419 IS3 family transposase -
QA637_RS25810 (QA637_25810) 1541840..1541977 + 138 WP_283067392.1 hypothetical protein -
QA637_RS25815 (QA637_25815) 1542048..1542383 - 336 WP_283065568.1 hypothetical protein -
QA637_RS25820 (QA637_25820) 1542451..1542774 - 324 WP_283065570.1 DUF736 family protein -
QA637_RS25825 (QA637_25825) 1543776..1544036 + 261 WP_283065572.1 antitoxin Antitoxin
QA637_RS25830 (QA637_25830) 1544033..1544437 + 405 WP_283065574.1 type II toxin-antitoxin system VapC family toxin Toxin
QA637_RS25835 (QA637_25835) 1545082..1546023 - 942 WP_283065576.1 DUF2493 domain-containing protein -
QA637_RS25840 (QA637_25840) 1546407..1547444 - 1038 WP_283065578.1 toprim domain-containing protein -
QA637_RS25845 (QA637_25845) 1547460..1547786 - 327 WP_283065580.1 hypothetical protein -
QA637_RS25850 (QA637_25850) 1547972..1548237 + 266 Protein_1428 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB / katA 1..2093508 2093508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(8-43)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14403.47 Da        Isoelectric Point: 5.6844

>T276510 WP_283065574.1 NZ_CP121660:1544033-1544437 [Sinorhizobium terangae]
VISHLLDTNAVIALIGRKSDTLVSRVLDSPQGSIGLPSVVAYELYFGAQRSAKVQHNLETLRLLMADFPILDFDQNDAFV
AGAIRAALAAKGTPIGPYDVLIAGQAKARGLTLVTNNGGEFNRVENLRVEDWSL

Download         Length: 405 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9862.07 Da        Isoelectric Point: 4.6768

>AT276510 WP_283065572.1 NZ_CP121660:1543776-1544036 [Sinorhizobium terangae]
MPHLARVFQSGNSQAVRLPKEFRFNVDRVEITPEGDALILRPHVEEAEPWSSLKAALVRGMSEDFMESGREQPEQQDRPD
IDAVFR

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References