Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-Xre |
| Location | 379665..380605 | Replicon | plasmid pCB3126_1 |
| Accession | NZ_CP121660 | ||
| Organism | Sinorhizobium terangae strain CB3126 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | QA637_RS20520 | Protein ID | WP_283067283.1 |
| Coordinates | 380114..380605 (+) | Length | 164 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | QA637_RS20515 | Protein ID | WP_283066566.1 |
| Coordinates | 379665..380036 (+) | Length | 124 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QA637_RS20490 (QA637_20490) | 375446..375829 | + | 384 | WP_283066557.1 | RidA family protein | - |
| QA637_RS20495 (QA637_20495) | 375847..377835 | + | 1989 | WP_283066559.1 | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | - |
| QA637_RS20500 (QA637_20500) | 377832..378701 | + | 870 | WP_283066561.1 | hydroxymethylglutaryl-CoA lyase | - |
| QA637_RS20505 (QA637_20505) | 378698..379480 | + | 783 | WP_283066563.1 | crotonase/enoyl-CoA hydratase family protein | - |
| QA637_RS20510 (QA637_20510) | 379505..379666 | - | 162 | WP_283066564.1 | hypothetical protein | - |
| QA637_RS20515 (QA637_20515) | 379665..380036 | + | 372 | WP_283066566.1 | DUF2384 domain-containing protein | Antitoxin |
| QA637_RS20520 (QA637_20520) | 380114..380605 | + | 492 | WP_283067283.1 | RES family NAD+ phosphorylase | Toxin |
| QA637_RS20525 (QA637_20525) | 380643..381164 | - | 522 | WP_283066567.1 | L-2-amino-thiazoline-4-carboxylic acid hydrolase | - |
| QA637_RS20530 (QA637_20530) | 381204..382571 | - | 1368 | WP_283066568.1 | FAD-binding oxidoreductase | - |
| QA637_RS20535 (QA637_20535) | 382571..383680 | - | 1110 | WP_153439904.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| QA637_RS20540 (QA637_20540) | 383696..384583 | - | 888 | WP_283066569.1 | sulfate ABC transporter permease subunit CysW | - |
| QA637_RS20545 (QA637_20545) | 384573..385430 | - | 858 | WP_283066570.1 | sulfate ABC transporter permease subunit CysT | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Conjugative plasmid | - | htpB / katA | 1..2093508 | 2093508 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 164 a.a. Molecular weight: 18234.83 Da Isoelectric Point: 6.4874
>T276508 WP_283067283.1 NZ_CP121660:380114-380605 [Sinorhizobium terangae]
MPLWRAFVPRWAHVPLSGEGAARFGGRWNPVGMPTIYAARELSTAWAEYNQGFVQHPALIVRLELYDARLADLTDAHVLE
ELGLTDAIHRCEWRDDLDKGAVPQTHKLQADLLAREFHGVIYPSFMSPGGTCVALWRWNGAGAPRLEVIDPEGRLPKSPA
SWL
MPLWRAFVPRWAHVPLSGEGAARFGGRWNPVGMPTIYAARELSTAWAEYNQGFVQHPALIVRLELYDARLADLTDAHVLE
ELGLTDAIHRCEWRDDLDKGAVPQTHKLQADLLAREFHGVIYPSFMSPGGTCVALWRWNGAGAPRLEVIDPEGRLPKSPA
SWL
Download Length: 492 bp
Antitoxin
Download Length: 124 a.a. Molecular weight: 13087.25 Da Isoelectric Point: 10.0414
>AT276508 WP_283066566.1 NZ_CP121660:379665-380036 [Sinorhizobium terangae]
MVALNLDIPAARFGEDHSPFLSARLVADRLGITLAELAKLIGVARNTLTAKSGARKVDSALSRVVRILAMASEMAGDEAR
AVIWFKHQPIPGWAGKTAFDLVGEGKADKVLAYLEAVRAGVYA
MVALNLDIPAARFGEDHSPFLSARLVADRLGITLAELAKLIGVARNTLTAKSGARKVDSALSRVVRILAMASEMAGDEAR
AVIWFKHQPIPGWAGKTAFDLVGEGKADKVLAYLEAVRAGVYA
Download Length: 372 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|