276507

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 173924..174564 Replicon plasmid pCB3126_1
Accession NZ_CP121660
Organism Sinorhizobium terangae strain CB3126

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA637_RS19530 Protein ID WP_153441708.1
Coordinates 173924..174310 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA637_RS19535 Protein ID WP_153441709.1
Coordinates 174310..174564 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA637_RS19500 (QA637_19500) 169383..169994 + 612 WP_184108609.1 hypothetical protein -
QA637_RS19505 (QA637_19505) 170027..170284 - 258 WP_283066350.1 DUF1127 domain-containing protein -
QA637_RS19510 (QA637_19510) 170387..171904 + 1518 WP_184108608.1 winged helix-turn-helix domain-containing tetratricopeptide repeat protein -
QA637_RS19515 (QA637_19515) 172102..172497 - 396 WP_283066352.1 GFA family protein -
QA637_RS19520 (QA637_19520) 172606..173073 - 468 WP_283066354.1 VOC family protein -
QA637_RS19525 (QA637_19525) 173467..173757 + 291 WP_153441707.1 DUF2934 domain-containing protein -
QA637_RS19530 (QA637_19530) 173924..174310 - 387 WP_153441708.1 type II toxin-antitoxin system VapC family toxin Toxin
QA637_RS19535 (QA637_19535) 174310..174564 - 255 WP_153441709.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QA637_RS19540 (QA637_19540) 174887..175567 - 681 WP_153441710.1 5-formyltetrahydrofolate cyclo-ligase -
QA637_RS19545 (QA637_19545) 175589..176755 - 1167 WP_283066357.1 cystathionine gamma-synthase -
QA637_RS19550 (QA637_19550) 176803..177438 - 636 WP_283066359.1 peroxiredoxin -
QA637_RS19555 (QA637_19555) 177600..178451 + 852 WP_153441713.1 LysR family transcriptional regulator -
QA637_RS19560 (QA637_19560) 178483..178779 - 297 WP_283066360.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB / katA 1..2093508 2093508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14018.93 Da        Isoelectric Point: 4.6381

>T276507 WP_153441708.1 NZ_CP121660:c174310-173924 [Sinorhizobium terangae]
MVIDTSAIVAVAFNEPEAETYERKVIDAPRRFISAATVLELAIVIEARLGEAGAAELDLWLYKAGVEIVAVDAEQIAVAR
RAWRSYGKGRHPAGLNYGDCFSYALAKTRNEPLLFKGDDFSRTDIEAA

Download         Length: 387 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9489.75 Da        Isoelectric Point: 6.3783

>AT276507 WP_153441709.1 NZ_CP121660:c174564-174310 [Sinorhizobium terangae]
MPLSIKDPETERLAKALAEKTGETITMATRRALEERLRRLANAANRDVLLEELAASRRRWSKLPVLDNRSADEILGYDEN
GTPN

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References